Determination of Cyanuric Acid in Milk Powder by Anion-Exchange Chromatography

The separation was achieved within 15 min on an anion-exchange column with simple elution of Na₂CO₃ / NaHCO₃ buffer as mobile phase. Furthermore, the effect of the total concentration of Na₂CO₃ / NaHCO₃ buffer on the retention of five inorganic anions was more obvious than that on CA retention, which indicated that CA retention on anion-exchange column depends not only on anion-exchange interaction but also on hydrophobic interactions between CA and anion-exchange column. The linear range of the calibration curve for CA was 0.1-100 mg L^-1. The detection limit calculated at S/N = 3 was 0.083 mg L-¹. The method was successfully applied to the analysis of CA in milk powder.

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