New Markers for Forensic Body-fluid Identification
Micro-RNAs (miRNAs) are a class of small noncoding RNA (ncRNA) molecules with a length of 18–24 nucleotides which play an essential regulative role for many cellular processes. Evidence suggests that the miRNome is a more precise and meaningful representation of a cell type and condition than the mRNA transcriptome. To identify miRNAs that are suitable for forensic body-fluid identification, a global screening by microarray analysis of c. 800 miRNAs of forensic blood and saliva samples was performed, and by bioinformatic processing, three differentially expressed candidate miRNAs for saliva and blood each were selected. The six candidates were then validated and confirmed via quantitative PCR. Herein, we present miRNA assays consisting of three differentially expressed miRNAs for the identification of blood (miR-126, miR-150, miR-451) and saliva (miR-200c, miR-203, miR-205), respectively. We conclude that miRNA extraction from forensic samples is possible and support a “proof of concept” that body-fluid identification by miRNA analysis may become a potent forensic technique.
Please note: The content above may have been edited to ensure it is in keeping with Technology Nteowrks' style and length guidelines.
Courts, C., & Madea, B. (2011). Specific Micro-RNA signatures for the detection of saliva and blood in forensic body-fluid identification. Journal of Forensic Sciences, 56(6), 1464–1470. doi:10.1111/j.1556-4029.2011.01894.x
Compact Chemical Sensor Can Detect Substances from Over 100 Feet AwayNews
A chemical sensor prototype developed at the University of Michigan will be able to detect "single-fingerprint quantities" of substances from a distance of more than 100 feet away, and its developers are working to shrink it to the size of a shoe box. The development offers great potential for medical and law enforcement purposes.READ MORE
New Rapid Authentication Test for Chinese MedicinesNews
Scientists have developed a new method for rapid and simple authentication of Chinese herbal medicines. The new method will enable authentication of genuine and counterfeit products, classification of wild and cultivated types, as well as differentiation of geographical origins.READ MORE