Using ‘Bacteria-Eaters’ to Prevent Infections on Medical Implant Materials
News May 13, 2013
Viruses that infect and kill bacteria — used to treat infections in the pre-antibiotic era a century ago and in the former Soviet Union today — may have a new role in preventing formation of the sticky “biofilms” of bacteria responsible for infections on implanted medical devices. That’s the topic of a report in the ACS journal Biomacromolecules.
Marek Urban and colleagues explain that bacteriophages (literally, “bacteria eaters”) were first used to treat bacterial infections in the 19th century. These viruses — more than 1,000 different kinds exist — attack disease-causing bacteria. The scientists focused on use of phages to wage “microbial warfare” on the films of bacteria that form on catheters, stents and other medical implants. These infections, which often involve antibiotic-resistant bacteria, strike more than a million patients annually in the United States alone, increasing hospital bills by almost $1 billion.
They describe attachment of phages to the surfaces of materials like those used in implanted medical devices, and evidence that the phages remain active, killing E. coli and Staphylococcus aureus. Those bacteria cause the most common hospital-acquired infections. The technology can attach phages to almost any surface, and is “a promising and effective means of not only combating antibiotic-resistant infections, but also the technological platform for the development of bacteria sensing and detecting devices.”
Natural Treatment Alternative to Formaldehyde Eliminates Germs From Hatching EggsNews
Hatching eggs in large-scale hatcheries are currently treated with formaldehyde to eliminate germs. Researchers have now developed a natural alternative.READ MORE
Nanosensor Could Help Prevent Food-borne IllnessesNews
To help prevent illnesses caused by bacteria in food or water, researchers have developed a new nanosensor to rapidly detect its presence.READ MORE