Depression, Anxiety and Apathy in Young-Onset and Atypical Dementia: A systematic review

Depression, anxiety and apathy are among the most frequent neuropsychiatric symptoms (NS) in typical Alzheimer’s disease, and impact quality of life, risk of institutionalisation, and caregiver burden. However, prevalence in atypical and young-onset phenotypes remains unknown.

This study aims to examine the body of empirical studies investigating the prevalence of depression, anxiety, and apathy in atypical and young-onset dementia.