Overcoming the Challenges of Analysing Ionic Polar Pesticides in Food
Poster Nov 03, 2017
Benjamin Wuyts, Euan Ross, Dimple Shah, Simon Hird, Gareth Cleland.
Glyphosate, a non-selective broad spectrum herbicide, accounts for more than half of global herbicide sales. While discussions on the toxicological concerns of glyphosate and associated compounds continue, maximum residue limits (MRLs) are enforced globally, requiring continued analytical testing to ensure consumer safety. In previous work, various methodologies have been presented, looking at underivatised options for the direct analysis of polar pesticides in food. [Scan the QR code below to discover more] Here, the novel application of the Waters’ Torus DEA column is presented, showing the improved performance of a UPLC-MS/MS method for the underivatised analysis of glyphosate and a selection of other anionic pesticides. Separation is achieved under Hydrophilic Interaction Chromatography (HILIC), after a simple column conditioning to activate the mechanism. Preliminary method performance, in the absence of isotopically labelled internal standard is summarised, in accordance with relevant SANTE 11945/2015 guidelines.
Development and Assessment of Non-Infected and Infected Skin Models Using MALDI-MSIPoster
Infections have detrimental effects on wound healing leading to chronic wound formation. The use of labskin,a living skin model, in combination with mass spectrometry imaging, provides a good model for assessing wound healing factors.READ MORE
LC-SWATH/MS Metabolomics Platform with Hyphenation of Extraction for the Analysis of Polar and Non-polar Metabolites in Biological SamplesPoster
Automated robotic sample preparation with hyphenated dual LC-SWATH/MS analysis for lipids and polar metabolites.
The Use of Pyrolysis/GCMS and Newly Developed Libraries to assist in Characterizing Complex Polymeric SamplesPoster
Pyrolysis-GC/MS is an effective tool in introducing and analyzing polymers. But since the polymer must be broken down to volatile segments in order to be sent to the GC, identification by the Mass Spec does not look at the original polymer, but only the fragments. This poster will look at a unique library designed to work with the existing NIST library, however contains averaged spectra of pyrolyzed polymers so it can be used to directly identify the original polymer sample.READ MORE