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Mettler Toledo Thornton Publishes White Paper

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Mettler Toledo Process Analytics Division has announced the publication of a white paper entitled “Improving Water System Performance - Continuous Real-Time TOC Measurements.”

This paper discusses the importance of rapid, continuous and reliable TOC (total organic carbon) measurement and control for critical water release in pharmaceutical manufacturing.

In pharmaceutical production, the accurate measurement of water quality is critical to the water purification process.

In fact, the FDA’s Process Analytical Technology (PAT) initiative promotes the use of real-time measurements with the objective of ensuring good product quality.

The pharmaceutical industry mandates monitoring of TOC as specified in the monographs of the United States Pharmacopoeia (USP) and in the European Pharmacopoeia (EP) for Purified Water (PW) and Water for Injection (WFI), as well as Highly Purified Water (HPW).

A Real Time Release continuous flow TOC sensor provides rapid response in real time to respond to and divert contaminated water, ensuring end users are receiving good quality water for production.

This allows Real Time Release (RTR) of product and leads to a more efficient operation.