Biomarkers – News and Features

A blood test promises to improve endometriosis diagnosis. By identifying a panel of 10 protein biomarkers, the test achieves high accuracy for early and severe cases, potentially replacing invasive diagnostic procedures like laparoscopy.

UK Biobank's proteomics study will measure 5,400 proteins in 600,000 samples, tracking changes over mid-to-late life. By combining genetic, imaging and proteomic data, this initiative promises breakthroughs in disease diagnosis and drug discovery.

A study reveals a genetic signature of 177 genes shared across cancers that drives metastasis. This pan-cancer breakthrough identifies two key genes, SP1 and KLF5, influencing metastasis progression.

A study reveals that adolescent rats fed a high-fat diet show altered brain development, impulsive actions, and cautious decision-making in adulthood. These changes link dietary patterns to modifications in the reward pathway and gut metabolism.

Researchers have shown that a test called ORACLE can predict lung cancer survival at the point of diagnosis better than currently used clinical risk factors.

A first-of-its-kind AI platform could help clinicians assess whether an individual will benefit from a particular therapy in clinical trials.

NYU researchers found that declining acetyl-L-carnitine and free carnitine levels correlate with Alzheimer’s severity, especially in women. These molecules track amyloid beta and tau protein levels, enabling highly accurate diagnosis.

Doctors around the world may soon have access to a new tool that could better predict whether individual cancer patients will benefit from immune checkpoint inhibitors — a type of immunotherapy — using only routine blood tests and clinical data.

Researchers from South Korea developed a novel microbial source tracking method using CrAss-like phages, abundant viruses in the human gut. Their DNA-based approach accurately detects human fecal contamination in water.

A University of Queensland study shows no link between childhood exposure to fluoridated water and negative cognitive outcomes. Researchers assessed IQs of 357 participants aged 16–26 and found no adverse effects.