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Cancer Immunology – News and Features

A person looks down from space towards the Earth.

The Next Chapter of Science

Join us as we explore how innovation, ethics and even aesthetics look set to influence the landscape of life science research, creating new possibilities for treating human diseases, feeding our growing population and nurturing the scientists of the future.
Two researchers in a lab.

Study Paves the Way for More Effective Liver Cancer Immunotherapies

A research team of Canadian and French scientists, led by INRS professor Maya Saleh, has been investigating immunotherapy resistance in certain patients with hepatocellular carcinoma (HCC) associated with steatotic liver disease.
Pink pills spill from a prescription bottle.

Cocaine Addiction Drug Could Pave Way for Colon Cancer Treatment

Vanoxerine, a drug initially developed to treat cocaine addiction, has also shown promise for advanced colon cancer in a new study.
Lung cancer cells.

Novel Combination Therapy Effective in Treating Immunotherapy-Resistant Lung Cancer

Phase II trial finds durvalumab plus ceralasertib boosted immune response and improved outcomes in patients with lung cancer.
Cell therapy.

Novel Design Improves CAR T-Cell Therapy for Childhood Leukemia

Scientists at St. Jude Children’s Research Hospital improved bispecific chimeric antigen receptor (CAR) T–cell immunotherapies for acute myeloid leukemia (AML), corroborated by computational analysis.
Computer-generated image of cells.

Risk of Secondary Cancer Investigated After CAR T-Cell Therapy

A study by University of Pennsylvania researchers shows that secondary cancer development is rare after CAR T-cell therapy and that many patients have achieved long-lasting remission.
T cells.

Technique Makes T Cells 100 Times More Potent at Killing Cancer Cells

Current immunotherapies work only against cancers of the blood and bone marrow. T cells engineered by Northwestern and UCSF were able to kill tumors derived from skin, lung and stomach in mice.
Stem cells.

Using Stem Cells To Enhance Cancer Immunotherapy Without Genetic Modification

A joint research team has used stem cells to generate human immune cells for application in cancer immunotherapy. This breakthrough platform is expected to significantly enhance cancer-targeting efficacy.
Cancer cells.

Discovery Could Lead to “Double Blow” Against Cancers

A multinational team of researchers led by Columbia University has discovered that tumors can repurpose a single cellular protein to hide themselves from the immune system in two distinct ways.
Two blood test vials held in a gloved hand.

Blood Tests Could Predict Poor CAR T-Cell Therapy Outcomes

Blood tests could predict outcomes of CAR T-cell therapy, helping to optimize cancer treatments and improve their safety and efficacy.