Cancer Immunology – News and Features

Researchers at the University of Chicago Medicine identified vitamin E succinate (VES) as an effective agent in suppressing tumor growth by promoting FTO degradation. This enhances T-cell cytotoxicity and improves response to immunotherapy.

Researchers have identified the transfer of mitochondria with mutated DNA from cancer cells to immune cells as a key mechanism of immune evasion and resistance to immunotherapy.

UVA Cancer Center researchers have explained the failure of immune checkpoint therapy for ovarian cancer by discovering how gut bacteria interfere with the treatment.

Researchers have developed a new avenue to reprogram compromised immune cells to act against tumors. The findings highlight a potential path forward for treating late-stage tumors that have become resistant to current therapies.

Researchers discover that bone marrow cancer cells diversify drastically when exiting the bone marrow, which also affects the immune cells in the cancer lesions. The new findings could contribute to more precise diagnostics and therapy.

Results published in the Journal of Crohn's and Colitis revealed that an antibiotic called vancomycin may also be effective in treating people with a specific type of inflammatory bowel disease (IBD).

A type of aggressive, treatment-resistant brain tumor has a distinct population of immune cells that support its growth, a new study has found.

Researchers have identified how a genetic flaw in some lung cancers alters cancer cell metabolism to fuel the disease.

A new study reveals that modifying the CUL5 gene enhances CAR-T cell therapy for leukemia and lymphoma. This improves cell longevity and tumor-fighting power, reducing cancer relapse.

Pancreatic cancer patients may benefit from future precision treatments as a new study shows how some tumors may potentially be more susceptible to macrophage-based therapies.