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Cancer Immunology – News and Features

Cancer cells.
News

Nanoparticles Stimulate Pathway in Immunologically “Cold” Tumors

A nanoparticle-based therapy developed by UT Southwestern Medical Center scientists stimulated an immune pathway that eradicated tumors in mouse models of various cancer types.
Cancer cells.
News

Mutation Behind Leukemia Cell Therapy Resistance Identified

Researchers at the University of Zurich and the University Hospital Zurich have discovered that a specific mutation in the cancer cells of an aggressive type of blood cancer can prevent novel immunotherapies such as CAR T-cell therapy from working.
Cancer cells.
News

Cell Therapy Approach Could Be Key for Rare Liver Cancer

Findings from scientists at St. Jude Children’s Research Hospital and The University of Tennessee Health Science Center suggest T-cell therapy could effectively treat fibrolamellar carcinoma.
Artistic representation of an antibody-producing plasma cell helping to fight invading pathogens.
Article

B Cells, Memory B Cells and Plasma Cells: B Cell Activation, Development and the B Cell Receptor

The adaptive immune system is highly specific. In this article, we focus on B cells, and discuss their development, their roles and what happens when they don’t function as they should.
T cells.
News

Why Do Some Immune Cells Lose Energy in Solid Tumors?

New research has unveiled new clues behind T-cell metabolism, that could enhance immunotherapies that rely on T cells to fight cancer.
A scientist behind a screen.
News

Dual Anti-Tumor Vaccine Approach Developed

A research team has discovered that exosomes derived from γδ-T cells not only have direct anti-tumour effects but also, when developed into a tumour vaccine, can effectively induce a tumour-specific immune response.
A syringe filled with liquid is balanced on two empty syringes.
News

“Dramatic” Brain Cancer Regression in Early Results of Cell Therapy Trial

Just days after a single treatment of a new cell therapy, three glioblastoma patients experienced dramatic reductions in their tumors.
Cell therapy.
News

Targeting Dual Proteins Shows Promise in Reducing Tumor Growth

Targeting two brain tumor-associated proteins—rather than one—with CAR T cell therapy shows promise as a strategy for reducing solid tumor growth in patients with recurrent glioblastoma (GBM), an aggressive form of brain cancer.
Representation of DNA.
Article

Genetic Tuning: The Next Frontier of Genetic Medicine

Discover how genetic tuning differs from gene editing and other modalities of genetic medicine and how the ability to fine-tune genes will transform precision medicine.
Cancer cells.
News

Understanding Breast Cancer Immune Escape May Lead to Treatment Pathway

A recent University of Kentucky Markey Cancer Center study published in PNAS uncovers a critical pathway involved in immune evasion by breast cancer cells.
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