Cancer Immunology – News and Features

Pathogen-fighting immune cells go through a surprising transformation and relocation as they fight infections in the gut.

Researchers have pinpointed a biological mechanism that strengthens the evidence that M. morganii influences brain health.

A study reveals children’s immune systems react differently to cancer than adults, with weaker immune activation due to fewer tumor mutations. This highlights the need for personalized pediatric immunotherapies focusing on immune activation.

Ultrasound-directed microbubbles could be used to influence the behavior of cancer-fighting T cells, reinvigorating the anti-tumor response.

Researchers at the Salk Institute discovered that targeting bile acid pathways can enhance liver cancer treatment. By reducing BAAT protein and supplementing with UDCA, they improved T cell function and controlled tumor growth in mice.

A new type of off-the-shelf cell-based immunotherapy shows promise for B-cell lymphomas, and could make make future cellular immunotherapies less expensive and more accessible.

UNC Lineberger researchers discovered a three-drug cocktail that enhances the production of T-memory stem cells (TSCMs) in CAR-T therapy, improving immune cell persistence and anti-tumor activity.

Researchers have identified the gateway for neuro-invasion in Semliki Forest virus infection, potentially enabling it to be used as an oncolytic virotherapy for brain cancer.

A study reveals that the way cancer cells die after radiotherapy depends on DNA repair methods. By blocking specific repair pathways, scientists can prompt immune responses against cancer cells.

A study finds that a sensitive test detecting circulating tumour DNA (ctDNA) in early-stage lung cancer can predict relapse risk and survival. This approach could help doctors personalize treatment and improve patient outcomes.