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Cancer Immunology – News and Features

Representation of DNA.

Genetic Tuning: The Next Frontier of Genetic Medicine

Discover how genetic tuning differs from gene editing and other modalities of genetic medicine and how the ability to fine-tune genes will transform precision medicine.
Cancer cells.

Understanding Breast Cancer Immune Escape May Lead to Treatment Pathway

A recent University of Kentucky Markey Cancer Center study published in PNAS uncovers a critical pathway involved in immune evasion by breast cancer cells.

New Class of Artificial Intelligence Can Advance Cancer Research

Mayo Clinic researchers recently invented a new class of artificial intelligence (AI) algorithms called hypothesis-driven AI that are a significant departure from traditional AI models which learn solely from data.
Protein structure.

Molecular “Brake” Could Help Develop Cancer Immunotherapies

A molecular “snapshot” of a protein can be critical to understanding its function. Scientists at Stanford and NYU have published and investigated a new structure of the protein LAG-3 which could enable the development of new cancer treatments.
A 3D model of human lungs.

Machine Learning Predicts Lung Cancer Spread to Brain

Scientists trained a machine-learning algorithm to predict accurately brain metastasis using biopsy samples from early-stage non-small cell lung cancer patients.
Red Zika virus particles surround a gray cell.

Zika Virus Vaccine Approach Shows Promise for Brain Cancer Cells

Attenuated Zika virus from vaccines could be used to destroy brain cancer cells, as they naturally target rapidly proliferating cells over mature cells.
A graphic representing the human genome.

What’s the Latest in CRISPR Gene-Editing Technology?

Featuring research from the Doudna laboratory, the University of Harvard and the Center for Advanced Bioenergy and Bioproducts Innovation, this round-up piece discusses the latest research advancements in CRISPR technology.
A gloved hand holds a syringe filled with red liquid.

CAR T-Cell Therapy Shows Activity in Subgroup of Brain Tumor Patients

A CAR T-cell therapy for glioblastoma has demonstrated promising clinical activity in a Phase 1 trial.
A male patient with a doctor.

Understanding the Genetics of Male Breast Cancer

Male breast cancer represents less than 1 percent of all breast cancer cases each year. Unlike breast cancer in women, survival rates for men haven't significantly improved in the last 30 years, according to the National Cancer Institute.
Cell therapy.

Study Paves the Way for “Off-the-Shelf” Cervical Cancer Cell Therapy

Researchers from Japan demonstrate that gene editing can enhance the effectiveness of rejuvenated cytotoxic T lymphocytes for targeted immunotherapy.