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High-Throughput Screening – Multimedia

Targeting the cGAS-STING Pathway Using a Homogenous, HTS Compatible cGAS Activity Assay content piece image
Poster

Targeting the cGAS-STING Pathway Using a Homogenous, HTS Compatible cGAS Activity Assay

Download this poster to discover a novel approach for detection of cGAS activity.
Vaping News Roundup 2019 content piece image
Listicle

Vaping News Roundup 2019

How safe are the ingredients in e-cigarettes? Here we highlight some of the studies exploring e-cigarette safety, published during 2019.
Capture True 3D Cell Culture Insights content piece image
eBook

Capture True 3D Cell Culture Insights

Download this fascinating eBook to gain new insights using advanced high-throughput
and high-content imaging systems.
Identification of New Hit Compounds Using a High-Throughput Phenotypic Screen with SMA Patient iPSC-Derived Motor Neurons content piece image
Poster

Identification of New Hit Compounds Using a High-Throughput Phenotypic Screen with SMA Patient iPSC-Derived Motor Neurons

Spinal muscular atrophy (SMA) is an inheritable cause of infant mortality that is characterized by the loss of lower motor neurons and skeletal muscle atrophy. The degeneration of motor neurons is caused by insufficient levels of survival motor neuron (SMN) protein, which is encoded by two nearly identical genes SMN1 and SMN2. Most cases of SMA harbour homozygous deletions of the SMN1 gene and retain at least one copy of SMN2.
ALS Drug Discovery via High-Throughput Phenotypic Screening Using iPSC-Derived Human Motor Neurons content piece image
Poster

ALS Drug Discovery via High-Throughput Phenotypic Screening Using iPSC-Derived Human Motor Neurons

At BrainXell, we established new technologies to rapidly differentiate ALS patient induced pluripotent stem cells (iPSCs) into large quantities of neurons.
6 Drug Discovery Strategies content piece image
Listicle

6 Drug Discovery Strategies

Despite being a complex and interdisciplinary process, remarkable advances have been seen in many areas of drug discovery and design. There are now several drug discovery strategies available to drug discovery scientists in search of new, efficacious drugs.
Magnetic-microcontact printing based ECM nano-patterning allows homogeneous controlling of cell growth and behavior content piece image
Poster

Magnetic-microcontact printing based ECM nano-patterning allows homogeneous controlling of cell growth and behavior

Magnetic – microcontact printing of extracellular matrix proteins (ECM) results in cell microarrays (CMA) showing homogeneous cell growth and attachment on defined patterns. This greatly reduces bias in the analysis of cell responses to toxins, drugs or other stimuli.
4 Toxicology Approaches in Drug Discovery content piece image
Listicle

4 Toxicology Approaches in Drug Discovery

This list highlights four approaches used to assess toxicology within the field of drug discovery.
Four Laboratory Equipment and Technology Trends content piece image
Listicle

Four Laboratory Equipment and Technology Trends

Technology trends can greatly increase the capabilities of the laboratory. Here we highlight some of the most popular upcoming trends in the field.
Bioluminescent Assay for GTPases Allows Measurement of GTPase, GAP and GEF Activities content piece image
Poster

Bioluminescent Assay for GTPases Allows Measurement of GTPase, GAP and GEF Activities

We have developed a homogenous bioluminescent assay (GTPase-Glo) system to analyze these proteins in a simple, convenient “add-mix-read” format.
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