High-Throughput Screening – Multimedia

For this week's Teach Me in 10 video, we're joined by Richard Cuthbert, who discusses screening in Drug Discovery.

Read this listicle to discover recent advancements in fragment-based screening including fragment tailoring, affinity mass spectrometry-based fragment screening and computational approaches using fragments.

While the complexity of organoids remains challenging, technological advances are enabling organoids to be developed and monitored in an automated fashion, so that they can be exploited in high-throughput drug screening assays.

Affibodies are synthetic antigen-binding proteins. They offer many advantages over monoclonal antibodies, including smaller sizes, enhanced thermal stability and rapid refolding capability. These advantages make affibodies an attractive platform for the development of therapeutics, diagnostics and bioimaging technology.

Stem cells are increasingly being used in new and innovative ways to improve the drug discovery process – spanning academia, biotech start-ups and large pharmaceutical companies.

With growing concerns over a multitude of food risks, accurate and sensitive analytical tools are needed to ensure food safety. Liquid chromatography-mass spectrometry (LC-MS) has become an indispensable method for food safety testing and quality control, capable of detecting and quantifying even trace amounts of numerous contaminants and harmful species in food.

Download this app note to discover a system that provides high-speed and reproducible quantification, has broad compound coverage and is purpose built for incorporation into high-throughput screening workflows.

Fragment-based drug discovery (FBDD) is one of the most popular approaches for finding lead compounds and it is becoming more widely adopted by pharma companies. Access this eBook to learn about the advantages, applications and future prospects of FBDD.

Download this app note to learn more about automated patch clamp and the benefits of using it in drug discovery.

Learn how researchers use high-throughput screening (HTS) to determine whether existing drugs can be repurposed as possible treatments for COVID-19.