We've updated our Privacy Policy to make it clearer how we use your personal data. We use cookies to provide you with a better experience. You can read our Cookie Policy here.

Advertisement

High-Throughput Screening – Multimedia

Real Time Dual-Channel Multiplex SERS Ultradetection content piece image
Poster

Real Time Dual-Channel Multiplex SERS Ultradetection

Real time On-line multiplex SERS detection in a microfluidic device.
Novel Approaches to High-throughput Measurements of Replicative Lifespan in Yeast by Microfluidic Size Sorting and Genetic Engineering content piece image
Poster

Novel Approaches to High-throughput Measurements of Replicative Lifespan in Yeast by Microfluidic Size Sorting and Genetic Engineering

Development of a high-throughput screen utilizing a microfluidic device and a linearly growing yeast strain to simultaneously test the influence of various drugs on the replicative lifespan of yeast.
Enabling Epigenetics Studies from HTS to SAR : A Novel HTRF<sup>®</sup> Platform to Identify and Characterize Reader Domain Inhibitors content piece image
Poster

Enabling Epigenetics Studies from HTS to SAR : A Novel HTRF® Platform to Identify and Characterize Reader Domain Inhibitors

Discover a novel HTRF platform to identify and characterize the vast variety of epigenetic binding domain.
The Longest Way Round is the Shortest Way Home: HTS Assay Development for Complex Multi-domain Protein Kinases content piece image
Poster

The Longest Way Round is the Shortest Way Home: HTS Assay Development for Complex Multi-domain Protein Kinases

This study strongly supports the possibility to overcome the major bottlenecks in the production of long kinase recombinant forms, in order to perform drug discovery programmes with proteins more closely preserving the structural and functional properties of the native enzymes.
Side by Side: An Evaluation of 2D vs. 3D Cell Culture for High Throughput Screening in Drug Discovery content piece image
Poster

Side by Side: An Evaluation of 2D vs. 3D Cell Culture for High Throughput Screening in Drug Discovery

•3D cell culture has the potential to provide a more physiologically relevant model compared to standard tissue culture plastic.
•From a screening perspective the technology offers the possibility of more predictive drug responses but has an increased cost.
•The question: is it possible and, more importantly, is it worthwhile moving towards screening in High Throughput using a 3D model?
High Throughput Screening in the European Lead Factory content piece image
Poster

High Throughput Screening in the European Lead Factory

This paper describes workflows that have been implemented at the screening centre of the European Lead Factory and presents screening statistics on the first 18 months of operation.
Progressing 3D Spheroid Analysis into a HTS Drug Discovery Method content piece image
Poster

Progressing 3D Spheroid Analysis into a HTS Drug Discovery Method

3D Tumorspheroid models for improved predictivity in cancer drug discovery.
Gut Microbial Metabolites and Hepatic Xenobiotic Metabolism: A High Throughput Screening Approach content piece image
Poster

Gut Microbial Metabolites and Hepatic Xenobiotic Metabolism: A High Throughput Screening Approach

This poster highlights the combination of metabonomics and high throughput screening by the identification of gut microbial metabolites and a screening assay designed to determine their cytotoxicity to liver-like cell cultures.
Human Cardiomyocytes Derived from Induced Pluripotent Stem Cells: High Throughput and High Content Assessment of Cardiac Toxicity and Drug Efficacy by Monitoring Cytosolic Free Calcium Transients content piece image
Poster

Human Cardiomyocytes Derived from Induced Pluripotent Stem Cells: High Throughput and High Content Assessment of Cardiac Toxicity and Drug Efficacy by Monitoring Cytosolic Free Calcium Transients

Introduction of selected, pure human cardiomyocytes derived from induced pluripotent stem cell (hiPSCM) into a calcium transient imaging high throughput screening (HTS) assay to assess cardiotoxicity and drug efficacies.
High-throughput analysis of protein formulations by DLS content piece image
Poster

High-throughput analysis of protein formulations by DLS

High-throughput analysis of protein formulations by Dynamic Light Scattering (DLS): thermal stability, colloidal stability and a thermal anomaly in the colloidal stability parameter D1
Advertisement