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High-Throughput Screening – News and Features

Cancer cells.
News

First-of-its-Kind Cancer Drug Shows Anti-Tumor Activity in Animal Models

Behind the scenes, as tumors progress and gain resistance to treatment, a protein called YB-1 quietly gives directions. Now, researchers have developed a first-of-its-kind drug that inhibits YB-1, effectively silencing those orders.
Gloved hand holding a 96 well plate in front of a screen displaying qPCR amplification curves.
Article

qPCR vs dPCR: Choosing the Right PCR Technology To Suit Your Experimental Needs

How can you identify which technique is best suited to your research requirements? In this article, we explore the advantages of qPCR and dPCR, considering specific applications and deliverable metrics to help you choose the right technology to suit your experimental needs.
Ocular Fibrosis, 3D Cell Culture Image, spherical microscopy image with various colors.
Industry Insight

Bridging Academia and Industry: The Evolution of 3D Models in Drug Development

The industry's search for alternatives to traditional preclinical drug testing methods has led to a growing interest in the potential of three-dimensional (3D) in vitro models. To delve deeper into this subject, Technology Networks spoke with Madhu Lal-Nag, chief scientific officer at InSphero, a 3D in vitro model company with a mission to “modernize drug discovery in ways that inspire researchers everywhere to reach their full potential and fuel a new era of breakthrough therapies.”
A row of pipettes filled with red liquid
Article

High-Throughput Screening: Advances, Applications and Combined Approaches

In this article, we highlight various high-throughput screening strategies being used to interrogate large libraries of compounds and hear from researchers working to further streamline specific approaches to increase speed and improve quality and accuracy.
Various pills on a table with a magnifying glass over one, bringing into focus.
Article

Drug Repurposing Strategies, Challenges and Successes

In this article, we explore the evolution of drug repurposing from a serendipitous occurrence to a more formalized endeavor involving advanced computational approaches and bioengineered test beds, considering its advantages, challenges and successes.
A metallic-organic framework shown in small spheres assembled into a grid shape.
News

AI Identifies New Materials for Carbon Capture

Generative AI, machine learning and simulations have been used to identify environmentally friendly metal-organic frameworks that can selectively absorb carbon dioxide.
A collection of many different pills.
Industry Insight

Using AI To Get Medicines to Patients Faster

To find out more about AI in pharma, Technology Networks spoke with Roger Palframan, head of US Research and digital for Early Solutions at UCB.
Bacteriophages.
News

Bacterial Immune System Makes Them More Susceptible to Antibiotics

A research team has now shown how the immune system enhances the effect of specific antibiotics against the cholera pathogen Vibrio cholerae.
Scientist with an assay plate.
News

3D Atherosclerosis Model Enables High-Throughput Drug Screening

A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease.
A lab worker.
News

New Material Gulps Down Hydrogen, Spits It Out To Protect Fusion Reactor Walls

University of Wisconsin–Madison engineers have used a spray coating technology to produce a new workhorse material that can withstand the harsh conditions inside a fusion reactor.
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