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High-Throughput Screening – News and Features

Bacteriophages.
News

Bacterial Immune System Makes Them More Susceptible to Antibiotics

A research team has now shown how the immune system enhances the effect of specific antibiotics against the cholera pathogen Vibrio cholerae.
Scientist with an assay plate.
News

3D Atherosclerosis Model Enables High-Throughput Drug Screening

A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease.
A lab worker.
News

New Material Gulps Down Hydrogen, Spits It Out To Protect Fusion Reactor Walls

University of Wisconsin–Madison engineers have used a spray coating technology to produce a new workhorse material that can withstand the harsh conditions inside a fusion reactor.
Pipette tips transferring liquid to a multi-well plate.
Article

Revolutionizing High-Throughput Drug Screening With AI and Organoids

Thanks to the rise of AI, HTS for drug discovery is taking a more intelligent, computational approach, with tools that allow scientists to pinpoint the most promising drug candidates faster. Explore how this evolution will be further enhanced by a shift from 2D to 3D biological models such as organoids.
Two microfluidic chips
Article

A Guide to Organ-on-a-Chip

By replicating the microenvironment of human organs within microscale devices, OOAC technology has emerged as a powerful tool for understanding human physiology and disease mechanisms with unparalleled precision.
Representation of cells.
Industry Insight

Maximizing Cell Line Productivity and Efficiency

In this interview, Dr. Tabitha Bullock tells us about some of the key considerations in cell line development and how advances in technology are improving the efficiency and productivity of cell lines.
Oil droplets.
News

High-Throughput Mass Spectrometry Platform Enables In Situ Screening of Fatty Acid-Producing Strains

A high-throughput mass spectrometry platform has enabled the in situ screening of fatty acids, showing it to be an efficient tool for fatty acid biomanufacturing.
A strand of silver-gray colored DNA.
News

Genome’s “Master” Regulator Could Be Used To Enhance T-Cell Therapy

A single master regulator of the genome can be used to reprogram a network of thousands of genes in T cells and greatly enhance cancer cell killing.
Droplets of liquid falling from pipette tips into a multiwell plate.
Article

Extracting Meaningful Data With High-Throughput Drug Discovery Approaches

This article focuses on the use of high-throughput screening approaches in drug discovery and discusses the latest developments in this area.
Brown wheat field.
News

Yeast Accelerates the Discovery of Medicinal Compounds From Plants

Cornell researchers have harnessed the power of baker’s yeast to create a cost-effective and highly efficient approach for unraveling how plants synthesize medicinal compounds.
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