High-Throughput Screening – News and Features

Preliminary results of a study show that a novel, selective inhibitor of protein arginine methyltransferase 5 demonstrated antitumor activity in patients with advanced malignant solid tumors or B cell non-Hodgkin lymphomas.

Revvity announced its newly established Scientific Centre of Excellence in Cambridge, where scientists can outsource their research needs to Revvity experts. Technology Networks visited the site to learn more about how Revvity is supporting its customers in their drug discovery efforts.

A team of researchers has identified an existing cancer drug that could also be used to treat an aggressive subset of cancers.

Marrying microfluidics with automation can provide the necessary level of control to perform high‑throughput LNP formulation screening in a cost-effective and timely manner, and how this approach can accelerate the development of new nanomedicines.

A new study combines a deep learning model with CRISPR screens to control the expression of human genes in different ways.

Scientists at the North Carolina State University found that a chemical compound produced through the digestion of a common artificial sweetener causes damage to DNA.

A ground-breaking study has led to the development of a small molecule probe that could improve our understanding of an important cellular messenger.

This article explores the various screening technologies used in the development of therapeutic antibodies and outlines the recent advances in this area.

Researchers in Japan identify a compound that can prevent cisplatin-induced renal toxicity and improve the outcomes of cancer treatment.

Technology Networks had the pleasure of speaking with Walid A. Houry, professor of biochemistry at the University of Toronto, to find out about the discovery of compounds that can induce protease hyperactivation to kill cancer cells.