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Light Microscopy – News and Features

Stem cells.

Light Sheet Microscopy Offers New Insights on Stem Cell Fate

Researchers at Duke University have been making movies by peering at stem cells near the root’s tip and taking snapshots as they divide and multiply over time, using a technique called light sheet microscopy.
Bacteria growing on an agar plate.

Key to Targeting Antibiotic-Resistant Bacteria Lies in Their Biofilm Arrangement

Researchers had assumed that bacteria were arranged somewhat randomly in biofilms. New research shows that bacteria that form biofilms actually have a highly structured arrangement within those slimy matrices.
Three in-focus cells with many more out of focus behind them.

Cells Respond Quickly to Small Light-Induced Micro-Environment Movements

Cells can quickly detect and respond to minor changes in their environment, and their response is more complex than expected, reports new research.
A model of a human heart.

Discovery of Key Protein Interactions as Potential Heart Disease Biomarker

Investigators have discovered previously unknown protein interactions in the heart’s atrium that are critical for normal heart function. The findings highlight a novel mechanism for MyBP-HL in regulating atrial relaxation and function.
Transmission electron microscopy image of the nanorobots.

Nanorobots Reduced Bladder Tumors by 90%

The research, which was conducted on mice, demonstrates how these tiny nanomachines are propelled by urea present in urine and precisely target the tumour, attacking it with a radioisotope carried on their surface.
Cells dividing.

How Stem Cell Embryo Models Won Method of the Year

A collection of ingenious biological tools for studying the genesis of life has been awarded Nature Methods’ coveted Method of the Year award for 2023
The brain implant.

Transparent Brain Implant Captures Deep Neural Activity From the Surface

When placed on the surface of the brain, this thin, flexible implant enables researchers to capture high-resolution information about neural activity deep inside the brain without damaging its delicate tissue.
Two images, one showing how the infrared spectroscopy technique works, the other showing a protein structure.

Single Protein Observed Using Infrared Near-Field Optical Microscopy

Infrared near-field optical microscopy has been used to observe the "molecular fingerprint" of single proteins.
Illustration of gloved hands using scissors and tweezers to alter a DNA double helix.

Genetic Modification Techniques and Applications

Manipulating genetics has helped mankind in numerous ways. In this article, we consider genetic modification strategies, including genome editing and genetic engineering, the techniques used to achieve them and purposes to which they are applied.
Super resolution microscopy reveals two roundworm collagens labeled in red and green.

Advanced Microscopy Technique Investigates How Skin Layers Are Bound Together

Species throughout the animal kingdom feature vital interfaces between the outermost layers of their bodies and the environment. Intricate microscopic structures are known to assemble in matrix patterns.