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Multiomics – News and Features

Stem cells.
News

Gut Stem Cell Research Reveals Mistaken Cellular Identity

Two independent studies by Columbia scientists suggest that research into the gut’s stem cells over the past 15 years has been marred by a case of mistaken identity: Scientists have been studying the wrong cell.
DNA double helix with 5mC and 5hmC methylation modifications indicated.
Industry Insight

Picking Apart the Epigenome To Advance Cancer Research

Both genetic and epigenetic sample information is required to get the full picture. Six-base genome sequencing enables this without need of multiple techniques, laborious downstream data processing or data loss, and cancer research is benefiting.
A thin slice of part of a Sorghum bicolor shoot apex.
News

The Potential of Bioenergy Sorghum for Sustainable Biofuels

Bioenergy sorghum is an important resource for the production of biofuels and bioproducts. Researchers have been working hard to make this tall, drought-tolerant plant even more productive and resilient to harsh environmental conditions.
A child looking through a toy.
News

Genetic Risk Factors for Autism Linked to Distinct Cellular Changes

A new single-cell study from the PsychENCODE initiative links genetic risk factors to cellular changes in ASD brains. The research, published in Science, provides insight on the potential causal mechanisms behind ASD.
A girl sitting on a chair looking out a window.
News

PTSD and Depression Have Shared and Distinct Brain Molecular Dysregulations

McLean Hospital researchers uncovered both shared and distinct molecular changes across brain regions, genomic layers, cell types and blood in individuals with posttraumatic stress disorder (PTSD) and major depressive disorder (MDD).
Two doctors stitching a patient after surgery
News

How Cells React to Pig Heart and Kidney Transplants in Humans

Two new studies reveal changes at the single-cell level in the organs and recipients’ bodies before, during and after transplantation with genetically modified pig organs in decedents.
Microbes in the gut.
News

Gut Bacteria Boosts Cancer Immunotherapy in Mice

A new strategy uses gut microbes to help unlock immunotherapy’s untapped cancer-fighting potential.
A woman on a mat doing sit ups.
News

The Effects of Exercise Revealed at the Cellular Level

Prolonged physical activity in rats results in profound changes to RNA, proteins, and metabolites in nearly all tissues, providing clues to many human health conditions.
Dr. Sarah Teichmann standing next to a building and pond.
Article

From School Science Club to Cell Atlasing With Dr. Sarah Teichmann

In this interview, Dr. Sarah Teichmann shares insights into her research interests, the goals and progress of the HCA to date, as well as her thoughts on how women can begin and build successful careers in science.
Cancer cells.
News

Biomarkers Linked to Cell Therapy Response for Bone Marrow Tumors Identified

In a recent clinical study, researchers identified several biomarkers that are associated with the response to CAR T cell therapy in multiple myeloma, a malignant tumour disease in the bone marrow.
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