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RNA-Seq – News and Features

Double helix structure of DNA.
News

Inherited Genetic Variants Influence Cancer Cell Gene Expression

Researchers investigated the extent to which forms of genetic variation called germline or inherited structural variation influence gene expression in human cancers.
Cell therapy.
News

Study Paves the Way for “Off-the-Shelf” Cervical Cancer Cell Therapy

Researchers from Japan demonstrate that gene editing can enhance the effectiveness of rejuvenated cytotoxic T lymphocytes for targeted immunotherapy.
Various pills on a table with a magnifying glass over one, bringing into focus.
Article

Drug Repurposing Strategies, Challenges and Successes

In this article, we explore the evolution of drug repurposing from a serendipitous occurrence to a more formalized endeavor involving advanced computational approaches and bioengineered test beds, considering its advantages, challenges and successes.
Bright staining highlights VIP-expressing interneurons in this coronal cross-section of a mouse brain. The neurons may help drive glymphatic clearance of amyloid via the release of peptides.
News

How Does 40Hz Sensory Gamma Rhythm Stimulation Clear Amyloid?

Stimulating a key brain rhythm with light and sound increases peptide release from interneurons, driving clearance of Alzheimer’s protein via the brain’s glymphatic system, new study suggests.
The activity of Snhg11 (red) pictured in the dentate gyrus region of the hippocampus in mice.
News

Down Syndrome Memory Challenges Tied to Genome's "Dark Matter"

Researchers reveal that the Snhg11 gene is critical for the function and formation of neurons in the hippocampus. Experiments with mice and human tissues revealed the gene is less active in brains with Down syndrome.
Cancer cells.
News

New Study Unveils Proteogenomics Landscape of Small Cell Lung Cancer

Researchers reported the first large-scale study characterizing the proteomics and phosphoproteomics of small cell lung cancer (SCLC) clinical cohorts, providing a comprehensive picture of the proteogenomics landscape of SCLC.
Doctor holding a clipboard.
News

Magnolia Berry Compound Shows Promise for Colon Cancer in Preclinical Models

A new study has discovered a naturally occurring compound found in a fruit has the potential to be an effective alternative treatment for colon cancer.
A babies feet.
News

The Surprising Strength of Babies' Immune Cells

For a long time, it has been thought that a baby’s immune system is far weaker than that of an adult due to limited pathogen exposure. However, a recent paper, published in Science Immunology, has questioned these beliefs.
A cow.
News

Bulls Offer Insight Into Male Fertility

Researchers have found genes in the reproductive organs of bulls that influence fertility. The findings can be transferred to humans, as these genes are also present in men.
High-Throughput Chromosome Conformation Capture technology allowed scientists to detect bacteriophage-host infection networks and how they varied between dry and wet soil.
News

Unraveling Soil Microbial Dynamics Through Phage-Host Interactions

High-Throughput Chromosome Conformation Capture technology allowed scientists to detect bacteriophage-host infection networks and how they varied between dry and wet soil.
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