RNA-Seq – News and Features

Increased risk for anxiety may begin before birth, shaped by infection or stressful events during pregnancy, a new study details.

A new study reveals how rare variants of a gene called ABCA7 may contribute to the development of Alzheimer’s in some of the people who carry it.

MIT researchers created the first large-scale atlas combining gene expression and regulation in over 3.5 million brain cells. They found that Alzheimer’s disease involves a collapse of nuclear compartments and erosion of epigenomic information.

This article explores how immune biomarkers can predict disease risk, guide treatment choices and overcome challenges to advance personalized medicine.

Researchers have identified novel molecular mechanisms that help specialized T cells maintain long-term immunity in response to chronic infection and cancer.

A study suggests that the rapid evolution of certain human brain cells may help explain why autism is more common in our species than in other primates. The research found that genes linked to autism were strongly shaped by natural selection.

How rapidly gene expression in a single cell changes over time can provide insight into how cells might become more specialized. A new method incorporated spatial information to this measurement to improve understanding of gene expression changes.

Researchers at Niigata University used zebrafish with a ube3a mutation to study autism-related behaviours. They found that stressful environments heightened anxiety and reduced social interaction, while familiar settings improved behaviours.

Researchers at Osaka University have identified two transcription factors that contribute to the development of gut-resident memory T cells associated with Crohn’s disease, a chronic inflammatory disorder affecting the digestive tract.

A new study from the University of Sydney has revealed how type 2 diabetes directly alters the heart’s structure and energy systems, offering vital insights into why people with diabetes are at greater risk of heart failure.