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Structural Biology – News and Features

Male doctor speaking to a male patient.

Clearer Diagnostics, Improved Chances: The Big-Picture Impacts of Improved Cancer Diagnostic Testing

Explore how innovations in the cancer diagnostic space, particularly those focusing on simple but effective diagnostic methodologies, could make cancer screening and early detection more straightforward, improving access and outcomes for patients.
Cell therapy.

Novel Design Improves CAR T-Cell Therapy for Childhood Leukemia

Scientists at St. Jude Children’s Research Hospital improved bispecific chimeric antigen receptor (CAR) T–cell immunotherapies for acute myeloid leukemia (AML), corroborated by computational analysis.
Neuron shapes shown in gold.

A Novel Molecular Mechanism Related to Neuronal Death

New research has revealed a molecular pathway that regulates neural cell death and the transport of mitochondria, which could help identify new therapeutic targets against neurodegenerative disease.
A close up of a leaf.

Efficiently Unlocking Plant Sugars Could Lead to Biofuels and Medicines

Research from Lawrence Berkeley National Laboratory (Berkeley Lab) sheds new light on how to access the sugars locked up in plants to produce petroleum-free fuels, chemicals, and medicines.
Simulated image of an egg and sperm cell at fertilization.

Supercomputer Simulates Protein Complex That Initiates Human Fertilization

Researchers recently developed highly realistic simulations of the proteins on sperm and egg cells coupling together before they fuse. These findings enabled the research team to solve several mysteries of fertilisation at once.
Two proteins, one white and smaller, the other yellow and large.

“Molecular Highway” Construction Seen in Human Cells for the First Time

Researchers have captured the world’s first high-resolution images of the initial moments of microtubule formation in human cells.
Protein structure.

Computer-Aided Protein Design Yields Customizable Hydrogels

New research demonstrates a new class of hydrogels that can form not just outside cells, but also inside of them. The team created these hydrogels from protein building blocks designed using a computer to form a specific structure.
An artist's impression of a prion protein molecule.

Transmissible Alzheimer’s Disease: What Is a Prion?

A new study suggests that Alzheimer’s proteins may spread in a “prion-like” fashion. So, what is a prion, and how does this finding change what we know about Alzheimer's?
An insulin pen.

Sclerostin Crucial for Heart Health in Diabetes

A study involving the University of Granada (UGR) and published in the journal Cardiovascular Diabetology has shown that sclerostin plays a protective role against the development of atherosclerosis in patients with type 2 diabetes.
A 3D rendering of a brain on a purple background.

New Role for Memory-Forming Protein Discovered

A common protein in the brain that usually forms part of the proteasome also plays a role in regulating genes during memory formation, reveals a new study.