Therapeutic Antibodies – Multimedia

App Note / Case Study
Simple and Fast Tracking of Drug–Antibody Ratio Distribution
Antibody drug conjugates (ADCs) are biotherapeutics, composed of small molecule drugs conjugated to an antibody scaffold, that have very complex molecular structures.

Infographic
Facilitating Bispecific Antibody Drug Development Through Quality Control
This is especially critical for bispecific antibodies, which are regarded as the second generation of antibody cancer therapies.

Video
Single-Cell Isolation: When Art Is Not Enough
In this episode, we speak with Andris Abramenkovs, product manager of CellCelector technology at Sartorius.

App Note / Case Study
Monitoring Intact Light Chain of Therapeutic mAbs in Human Serum Using HRAM LC-MS
Download this tech note to learn how mass spectrometry has gained substantial popularity for therapeutic mAb monitoring in clinical laboratories due to its great versatility to detect both tryptic peptides and intact light and heavy chains quantitatively.

eBook
Your Guide To Efficiently Develop Antibody-Based Therapeutics
In the “Quality by Design” approach for monoclonal antibody (mAb)-based therapeutics development, stability characterization—the probability of a protein unfolding—is performed to ensure that structure and function are preserved throughout development and manufacturing.

App Note / Case Study
Automated Switching Between Peptide and Glycan Mapping
Glycan and peptide mapping are key analytical methodologies for the structural characterization of therapeutic proteins such as monoclonal antibodies (mAbs).

App Note / Case Study
Preclinical Quantification of Trastuzumab in Rat Plasma
In quantifying therapeutic peptides and proteins in biological matrices, traditional ELISA-only based techniques can suffer from high variability, narrow dynamic range, problems with selectivity and typically cannot use internal standards.

Video
Biopharmaceuticals: What They Are and How They Are Made With Professor Andrew Zydney
In less than 10 minutes, Professor Andrew Zydney covers: What are biopharmaceuticals? How do they differ from traditional small-molecule pharmaceuticals? How are they made? What factors might influence the high cost of biopharmaceuticals?

Video
Antibody-Based Therapeutics Against Cancer: Emerging Targets and Research Tools
Speaking at The Landscape of Cancer Research 2021 online symposium, Tianzi Li delivered her talk on the discovery of novel targets and the use of antibodies in cancer therapy.

Infographic
A Roadmap to Antibody Drug Discovery
In recent years, therapeutic antibodies have become the predominant class of new drugs developed in order to combat different diseases including cancers and autoimmune diseases among others. Antibody drug discovery does not come without its challenges including screening, characterization and target identification.
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