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Vaccine Design and Testing – News and Features

Vaccine vials.
News

Researchers Identify Gene Behind HIV Vaccine Ineffectiveness

A study found a gene in human cytomegalovirus (HCMV) that can block immune responses needed for an effective HIV vaccine. This discovery could improve future vaccine designs for HIV and other diseases.
A microscope image showing how mRNA (labelled in red) is transfected across a mouse brain.
News

Could In Utero mRNA Therapy Fix Faulty Genes Before Birth?

A new mouse study shows how a new tool can deliver genetic material to edit faulty genes in developing fetal brain cells.
A pregnant person holds their baby bump.
News

Maternal Antibodies Disrupt Infants' Responses to Malaria Vaccines

Maternal antibodies passed across the placenta can interfere with the response to the malaria vaccine, explaining its lower efficacy in infant under five months of age.
Vaccine vials on ice.
News

mRNA Vaccine Provides Hope for Preventing C. difficile Infections

Researchers developed an mRNA vaccine that protects against C. difficile infections. The vaccine induces a strong immune response, promotes bacterial clearance, and shows potential for broader applications.
Bacteria under an electron microscope.
News

Personalized Probiotic Bacteria Vaccine Shows Promise as Cancer Immunotherapy

Researchers have created engineered probiotic bacteria that educate the immune system to attack cancer cells, showing promising results in mouse models. These personalized bacterial vaccines could lead to effective treatments for advanced cancers.
A needle poking into a vaccine vial.
News

Potentially Longer-Lasting Covid Vaccine Targets Identified

Researchers identified more than 200 new vaccine target candidates from SARS-CoV-2, focusing on seven viral proteins beyond the Spike protein. These candidates could enhance immunity by triggering T cell responses.
A strand of DNA.
News

Enzyme Engineered To Produce Threose Nucleic Acid, a Synthetic Genetic Material

Researchers have engineered an enzyme to produce synthetic genetic material, advancing the discovery of new therapeutics for cancer and autoimmune, metabolic and infectious diseases.
RNA Polymerase II transcribing DNA into RNA.
Industry Insight

Getting New Drug Modalities to Market: How Can Your Data Strategy Help?

This article explores the revolution in new drug modalities and the challenges around effective data strategies to support AI efforts.
A mug with a box of tissues beside it.
News

Previous COVID-19 Infections Protect Against Severe Cases of the Flu

Recovery from COVID-19 infection can have a protective effect against the worst effects of flu, and this memory response comes from an unexpected corner of the immune system.
A needle piercing the top of a vaccine vial.
News

Natural Immunity Enhances Response to Influenza Vaccines

A study reveals that natural immunity gained from previous influenza infections enhances immune responses to subsequent vaccinations. This finding suggests that individuals who contract the flu may benefit in their battle against future strains.
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