Vaccine Design and Testing – News and Features

An international study led by the Wellcome Sanger Institute and collaborators analyzed nearly 10,000 Haemophilus influenzae genomes, uncovering low global genetic diversity and extensive antibiotic resistance.

Washington University researchers discovered how yellow fever and tick-borne encephalitis viruses enter human cells and created decoy molecules that block infection, paving the way for new antiviral therapies.

Yale researchers have developed a new vaccine that does double duty against a rare and aggressive skin cancer by targeting the protein essential to tumor cell growth and by adding a key signal to boost the immune system response.

Enhancing continuous manufacturing of vaccines, researchers innovate a Raman spectroscopy tool for efficient quality control in production.

Researchers created a model for cutaneous squamous cell carcinoma, a type of skin cancer, and identified two mutated tumor proteins, or neoantigens, that contain features of good candidates for a vaccine.

A study reveals that mRNA vaccination near the start of immunotherapy nearly doubled survival in advanced lung and skin cancer patients.

A new early-stage clinical trial found that a novel monoclonal antibody provided dose-dependent full protection against the malaria parasite with minimal side effects.

Biologists are using a cutting-edge approach combining computer science with immunology to scan the genetic makeup of pathogens and predict which parts of them can trigger a strong immune response.

Researchers have demonstrated that their nanoparticle-based vaccine can effectively prevent melanoma, pancreatic and triple-negative breast cancer in mice.

Researchers have completed a successful Phase 1 clinical trial of a novel vaccine designed to protect against both typhoid fever and invasive non-typhoidal Salmonella.