Western Blot – News and Features

Industry Insight
Developing the World's First Single Molecule Protein Sequencer
Jagannath Swaminathan is the co-founder of Erisyon and a researcher at the Marcotte Lab at the University of Texas Austin. In this interview, we discuss the concept of next-generation protein sequencing, clinical proteomics and the critical role of protein sequencing in the fight against COVID-19.

Article
How FAIMS Is Changing the Game in Proteomics
Scientists explore proteomes to identify proteins, quantify their expression and analyze modifications. But proteome coverage and complexity are increasing, creating challenges for traditional profiling. Technologies based on high-resolution mass spectrometry, however, can overcome this, making them the method of choice in basic, translational and biopharmaceutical laboratories alike.

Article
Cancer Biomarkers: Powering Precision Medicine
Researchers are developing biomarker tests to detect cancer early, monitor therapeutic efficacy and predict outcomes – making diagnosis and treatment more precise.

Article
The Pursuit of Spotting and Steering Cell Death
Here, we examine one common branch of cell death, apoptosis, and explain why studying aberrations in apoptotic signaling is important for understanding and addressing a range of human pathologies. We also highlight techniques that enable studies of apoptosis.

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Who Will Win the "Race to the Bottom" in the Infectious Disease Testing Market?
When it comes to testing for infectious diseases, it seems some companies are engaged in a “race to the bottom” to provide the cheapest test possible. Ever-lower price points might be attractive for cash-strapped governments, NGOs and charities engaged in the ongoing fight against infectious diseases, but are such practices putting us at risk of compromising quality?

News
New Test Diagnoses Lyme Disease Within 15 Minutes
Rapid diagnostic test for Lyme disease matches and outperforms standard testing approaches; could be used in a clinician’s office.

Article
Mass Spectrometry Accelerates Protein Biotherapeutics Discovery and Assures Quality Control
To keep pace with the burgeoning biopharma market, research has also advanced antibody characterization and quality assurance. Protein biotherapeutics are inherently heterogenous and complex but techniques within the mass spectrometry field are meeting these challenges head on.

News
Senescent Cells May Play a Role in Thrombosis
Senescent cells may underlie clotting predisposition, suggest the findings from a recent study by researchers at the Buck Institute for Research on Aging.

Article
Why Does the Molecular Weight of My Protein Differ From the Theoretically Expected Weight?
The predicted protein molecular weight (MW) is the sum of all protein amino acid MWs. The calculated MW may be different from that observed on the Western blot. In this article, we summarize common reasons as to why this may occur.

Article
Multi-Modal PET Imaging Provides Novel Insights in Preclinical Oncology
The broad range of tumor types and their varying reactions to treatment make the search for new effective cancer therapies incredibly challenging. Non-invasive in vivo imaging technologies such as PET enable researchers to better understand the course of tumor progression, by visualizing cancer-related processes in real-time.
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