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Western Blot – News and Features

New Test Diagnoses Lyme Disease Within 15 Minutes content piece image
News

New Test Diagnoses Lyme Disease Within 15 Minutes

Rapid diagnostic test for Lyme disease matches and outperforms standard testing approaches; could be used in a clinician’s office.
Mass Spectrometry Accelerates Protein Biotherapeutics Discovery and Assures Quality Control content piece image
Article

Mass Spectrometry Accelerates Protein Biotherapeutics Discovery and Assures Quality Control

To keep pace with the burgeoning biopharma market, research has also advanced antibody characterization and quality assurance. Protein biotherapeutics are inherently heterogenous and complex but techniques within the mass spectrometry field are meeting these challenges head on.
Senescent Cells May Play a Role in Thrombosis content piece image
News

Senescent Cells May Play a Role in Thrombosis

Senescent cells may underlie clotting predisposition, suggest the findings from a recent study by researchers at the Buck Institute for Research on Aging.
Why Does the Molecular Weight of My Protein Differ From the Theoretically Expected Weight?  content piece image
Article

Why Does the Molecular Weight of My Protein Differ From the Theoretically Expected Weight?

The predicted protein molecular weight (MW) is the sum of all protein amino acid MWs. The calculated MW may be different from that observed on the Western blot. In this article, we summarize common reasons as to why this may occur.
Multi-Modal PET Imaging Provides Novel Insights in Preclinical Oncology content piece image
Article

Multi-Modal PET Imaging Provides Novel Insights in Preclinical Oncology

The broad range of tumor types and their varying reactions to treatment make the search for new effective cancer therapies incredibly challenging. Non-invasive in vivo imaging technologies such as PET enable researchers to better understand the course of tumor progression, by visualizing cancer-related processes in real-time.
The Way Forward for Antibodies in Neuroscience content piece image
Industry Insight

The Way Forward for Antibodies in Neuroscience

Antibodies are an essential part of everyday neuroscience research. But recently, high-profile criticism has cast doubt on their reliability and reproducibility. We caught up with Bio-Techne’s Raymond Chan and Katherine Bradley to find out how providers are hoping to improve antibodies and make them fit for a more reproducible future in neuroscience.
Entering the Antibody Lottery: Tips for Avoiding Dubious Sources content piece image
Industry Insight

Entering the Antibody Lottery: Tips for Avoiding Dubious Sources

Having reliable antibodies can make or break your assay. However, sourcing the right antibody for the job can sometimes feel like you’re entering the lottery: there are so many on the market, and often they just don’t live up to what was promised. To learn more about antibody validation and its importance, we got in touch with Anthony Couvillon, PhD, Scientific Marketing Project Manager at Cell Signaling Technology.
Antibodies in Research: The Good, the Bad, and the Validation Epidemic  content piece image
Article

Antibodies in Research: The Good, the Bad, and the Validation Epidemic

The specificity of antibody binding is incredibly important for many research disciplines, yet sourcing the best antibody for your research can be a challenge. This is partly because not all suppliers validate their antibodies sufficiently. How much of a problem is this?
Realizing the Potential of Top-down Proteomics content piece image
Article

Realizing the Potential of Top-down Proteomics

Having grown beyond early ‘proof-of-principle’ studies, top-down proteomics is now extensively used to analyze intact proteins in numerous applications. Here, we discuss how the top-down proteomics approach emerged, reasons underpinning its success, and highlight some of the most exciting current developments.
Case Study: Dr. Kaelberer Validates a Neuroepithelial Circuit using Milo content piece image
Article

Case Study: Dr. Kaelberer Validates a Neuroepithelial Circuit using Milo

How does the gut talk to the brain? In this new case study from ProteinSimple, we find out how Melanie Maya Kaelberer, a Postdoctoral Associate at Duke University, is using Single-Cell Western platform Milo to answer the question of how the gut can rapidly communicate with cranial nerves.
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