Detection of Endogenous Biomarkers in Complex Matrices
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Detecting the presence of endogenous biomarkers—such as corticosteroids and endocannabinoids—from nails and hair samples is central for diverse research areas, including stress-related disease and forensics.
However, these sample types present unique analytical challenges due to their keratinized structure and extremely low analyte concentrations.
This webinar highlights a sensitive LC-MS/MS workflow designed to enable reproducible quantification of endogenous biomarkers in keratinized matrices.
- Detect biomarkers in keratinized matrices at femtogram levels
- Maximize recovery and minimize background
- Calibrate and quantify different endogenous compounds