Generation and Characterization of Retinal Organoids From iPSCs

Professor Armstrong studied chemistry at the Universities of Sheffield and Northumbria and was awarded a PhD in physical organic chemistry in 1992. As an outcome of his PhD research into the chemistry of fluorescent molecules, he founded a contract research organisation developing and licensing diagnostic systems to identify and enumerate bacteria in biological fluids. This organisation was successful in generating a range of products that were subsequently licensed to industry and marketed as microbial diagnostic tools. Prof Armstrong’s highly respected research group is focussed on reprogramming cells to hiPSCs and developing organoid and other complex models of human tissues. A key aspect of this investigation is researching the possible reversal of ageing during the reprogramming process and how this might be valuable for repairing organ damage or treating human diseases using iPSCs.