Unlocking High-Value Targets: The Power of Chemoproteomics and Covalent Mass Spectrometry
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Covalent inhibitors are regaining attention in drug discovery for their enhanced potency, selectivity and their ability to tackle challenging targets.
Our expert speakers will showcase Evotec’s innovative strategy for identifying covalent hits using high-throughput mass spectrometry. By attending, you’ll learn how intact protein and peptide-based assays can rapidly highlight promising binders, precisely mapping their binding sites. Our speakers will also demonstrate the power of chemoproteomic profiling in live cells to validate target engagement and selectivity.
Join this webinar to discover how integrating these complementary approaches can reduce off-target risks, accelerate timelines and improve confidence in progressing from hit to lead – helping researchers strengthen their discovery pipeline.
- Explore the background of covalent inhibitors and their unique benefits in modern drug discovery
- Learn how high-throughput mass spectrometry (MS) accelerates covalent hit identification
- Gain an insight into site-specific analysis using peptide mapping and intact protein MS
- Take a dive into advanced chemoproteomic strategies for hit validation
