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Biosimilar Surge Driving Need for Antibody Characterization

Blog

Accurate protein characterization is particularly important in the biopharmaceutical industry, where product modifications can affect efficacy and safety. Here, we speak to Matthew Lauber, a consulting scientist who elaborates on the importance and challenges of biotherapeutic protein characterization, and discusses different techniques used for charge variant analysis.

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DeNovix CellDrop™ - Count Cells Without Slides

Video

Reduce plastic waste in your lab, eliminate disposable slide costs and automate cell counting in your lab with DeNovix CellDrop cell counters. Using DirectPipette™ Technology, CellDrop brings familiar load, measure and wipe clean ease-of-use to image-based cell counters.

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How did Lisa McPherson gain confidence in her pipetting?

Video

Watch to find out how Dr. Lisa McPherson, a Stanford researcher, made her days in the lab go better with electronic pipette Picus. Lisa discusses how making her pipetting efficient with Picus has enabled her to cut the time she spends on an assay in half. For her research, this means she can now do more assays and test more hypotheses.

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Pluripotent Stem Cells in Drug Discovery: Can We Stem the Tide of Unsuccessful Drugs?

Article

Stem cells were first discovered in human cord blood in 1978. Why would we think they can be of more help now? This article delves into reasons behind the sudden interest in stem cells, and highlights how they can be used to advance drug discovery.

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Answer the challenges of CDS Data integrity - Sterling Pharma Solutions Ltd

Webinar

Data integrity continues to be a hot topic for the regulatory agencies in the pharmaceutical industry.

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Evidence for Exosomes as Paracrine Mediators of Labor and Delivery

News

Exosomes are tiny vesicles derived from the invagination of the endosomal membrane and are released from cells into surrounding fluids. In this study, exosomes collected during either early or late pregnancy were injected into a separate group of pregnant mice during the human equivalent of the beginning of the third trimester.

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Possibilities for Stem Cell Therapy in Parkinson's Highlighted
News

Stem cell technologies show promise for treating Parkinson's disease and may play an increasing role in alleviating at least the motor symptoms, if not others, in the decades to come.

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Animal Venoms Aid the Search for New Medicines
News

Animal venoms are the subject of study at research center based at the Butantan Institute in São Paulo. But in this case, the idea is not to find antidotes, but rather to use the properties of the venoms themselves to identify molecular targets of diseases and, armed with that knowledge, develop new compounds that can be used as medicines.

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Immune Stimulant Molecule Protects Against Multiple Cancers
News

A research team at the University of Louisville has discovered that an immune checkpoint molecule they developed for cancer immunotherapy, also protects against future development of multiple types of cancer when administered by itself.

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How Genomics is Shaping Advanced Therapeutics
Article

Genomics technologies are guiding the development of advanced therapy medicinal products, i.e. gene-based, cell-based, and tissue-engineered approaches. This article highlights the progress, challenges and impact of this interdisciplinary branch of medicine.

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UK Lung Cancer Diagnostic Services: Time to Step Up
Article

The UK’s national health system needs to take a hard look at their priorities and procedures to ensure that rapid advances in molecular diagnostics in lung cancer are translated into a practical service for all patients, according to a report launched at the British Thoracic Oncology Group Annual Conference.

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Recent Advances in Liquid Biopsy for Cancer
Article

Liquid biopsies for cancer search for evidence of disease biomarkers, the most common of which include circulating tumor cells, cell-free nucleic acids, exosomes, proteins and phosphoproteins. Read on for insights on advances in the field that could revolutionize clinical oncology practice.

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A Renaissance for Microflow Liquid Chromatography Mass Spectrometry?
Article

First developed in the 1970s, recent developments are making microflow liquid chromatography techniques more robust – enticing researchers to revisit the opportunities it offers for more sensitive, high-throughput analyses requiring smaller sample volumes than standard flow techniques.

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Overcoming Challenges in Biopharma: Transformational Innovation is Key
Article

Looking at the industry growth and the complexities of biopharma development, it is no wonder that transformational developments are required to better equip laboratories and operations in biopharma.

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Quantifying Minimal Residual Disease in Chronic Myeloid Leukemia
Article

Thanks to advances in therapeutics, chronic myeloid leukemia has been transformed from a deadly cancer into a manageable, chronic condition. However, patients have to stay on these drugs their whole lives, as there isn't a diagnostic test sensitive enough to detect traces of the disease that threaten a relapse. This article delves into the unmet need for such a test, and explains why droplet digital PCR (ddPCR) is a strong candidate that may fill this gap.

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