Cancer Stem Cells Redefine How We Think About Cancer

Article

Cancer stem cells (CSC) can be difficult to define, even for biologists. In order to understand CSCs, cancer itself must be thought of as highly organized – comprised of cancer cells that have a cellular hierarchy.

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Answer the challenges of CDS Data integrity - Sterling Pharma Solutions Ltd

Webinar

Data integrity continues to be a hot topic for the regulatory agencies in the pharmaceutical industry.

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Simplify Your 3D Cell Culture with a Novel Method for Tissue Modeling

Video

This video shows the technology behind the RAFT™ 3D Cell Culture System and how it creates high-density collagen scaffolds with cells embedded. The RAFT™ System has successfully been used in many research areas including toxicology, oncology, blood brain barrier models, corneal models and more. Coming along with easy-to-follow protocols, RAFT™ System allows you to set up robust 3D cultures in less than an hour. Learn more about RAFT™ System on www.lonza.com/raft-3d-culture.com.

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6 Tips for Successful Transfection

List

The following is a list of what I think are the most useful tips for successful transfection, learned through years of experience and troubleshooting transfection experiments.

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How Environmental Pollutants and Genetics Work Together in Rheumatoid Arthritis
How Environmental Pollutants and Genetics Work Together in Rheumatoid Arthritis
News

It is well known that individuals with a particular version of human leukocyte antigen have an increased risk for rheumatoid arthritis, but there has been growing interest in the role of environmental pollutants. In a new mouse study, researchers probed the relationship between the two.

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Deficiency of Innate Immune Adaptor TRIF Linked to Neurodegeneration
Deficiency of Innate Immune Adaptor TRIF Linked to Neurodegeneration
News

Research has revealed that deficiency of the innate immune adaptor TRIF, which is essential for certain Toll-like receptor signaling cascades, significantly shortened survival time of ALS mice.

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New Process to Differentiate Stem Cells into Nucleus Pulposus-Like Cells
New Process to Differentiate Stem Cells into Nucleus Pulposus-Like Cells
News

Researchers at Washington University have developed a new way to transform human induced pluripotent stem cells into nucleus pulposus cells, which are the chief component of intervertebral discs.

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PhoreMost and Plexxikon Collaborate to Identify Novel Drug Targets
PhoreMost and Plexxikon Collaborate to Identify Novel Drug Targets
News

PhoreMost, the UK-based biopharmaceutical company dedicated to drugging ‘undruggable’ disease targets, today announced it has signed a collaborative agreement with Plexxikon Inc., the small molecule structure-guided R&D centre of Daiichi Sankyo.

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"Superplatelets" Could Help Make Trauma More Survivable
"Superplatelets" Could Help Make Trauma More Survivable
News

A University of British Columbia bioengineer has developed a potential strategy for endowing platelets with extra powers so they can rise to the occasion and continue coagulation.

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‘Bad’ Antibodies Provide Crucial Protection Against Invading Microbes
‘Bad’ Antibodies Provide Crucial Protection Against Invading Microbes
News

In a world first, scientists have revealed how a population of 'bad' antibodies in the immune system - which are usually 'silenced' because they can harm the body - can provide crucial protection against invading microbes.

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Relaxing the Tension Between Publishing and Patenting: The Legal Basis for Tension

Relaxing the Tension Between Publishing and Patenting: The Legal Basis for Tension

Article

Tension can be felt between the desire to publish and the need to patent, especially in commercially savvy environments such as medical technology and pharmaceuticals. This article discusses the legal rationale behind why publishing early can hinder future patenting opportunities and provides practical tips for avoiding this situation.

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Relaxing the Tension Between Publishing and Patenting: Practical Hints and Tips
Article

In Part 1 we outlined some patent-related ramifications of publishing your research and development prior to filing a patent application. This second part provides you with some practical hints and tips for drafting your paper, helping you to avoid potential issues that can arise.

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Novel Biotherapeutics for the Treatment of Cancer
Article

Immunotherapies might be stealing the show in cancer biotherapeutics, but it would seem that combining them with other biological agents – DNA or viruses, for example – is the way to seeing dramatic successes in more cancer patients.

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Discipline Convergence and the New Manufacturing Paradigm
Article

In many industries, curiosity-driven research is being replaced by purpose-driven research, as scientists must satisfy market-led specifications. Successful predictive science depends on seamless collaboration, unified workflows, comprehensive knowledge, and standardized data that is available and understandable in context.

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