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Protocol video: simple and efficient detection of mycoplasma contamination in cell culture

Video

EZ-PCR Mycoplasma Detection Kit designed for routine screening and detection of over 90 species of mycoplasma through an easy-to-use, yet highly-specific PCR assay with a detection limit of 10 CFU/mL.

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Top 10 Cell Science News Stories of 2019

List

2019 has been an exciting year for cell science. In this list, we look at ten of the most-read news stories published on Technology Networks this year.

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Biodegradable Nerve Guide Helps Regenerate Damaged Nerves
News

Scientists have created a biodegradable nerve guide consisting of a polymer tube filled with a growth-promoting protein, glial cell-derived neurotrophic factor, or GDNF. The results in nonhuman primate studies are promising.

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CRISPR Cuts Open New Avenues in CAR T-cell Therapy
News

According to a study published in the Blood journal, drug profiling and the CRISPR-Cas9 gene editing method have opened new avenues in the development of CAR T-cell therapy, used to treat leukaemia and lymphoma.

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Danger Posed by Whooping Cough Once More
News

Whooping cough bacteria, potentially deadly in infants, are increasingly evading immunity from the existing vaccine, strengthening calls for a new vaccine to be developed and deployed urgently.

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Progression of Eye and Cardiac Disease Halted by Food Supplement
News

UNIGE researchers have discovered a new gene that causes blindness and
cardiomyopathy. They have also managed to halt the progression of eye disease and treat cardiac disease by administering a food supplement.

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Studies Point to Important Role for B Cells in Promoting Anti-tumor Immunity
News

The likelihood of a patient responding to immune checkpoint blockade may depend on B cells in the tumor, located within specialized immune-cell clusters known as tertiary lymphoid structures (TLS), according to researchers at The University of Texas MD Anderson Cancer Center.

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Targeting “DNA Rewiring” To Reduce Breast Cancer Relapse
News

Epigenetic changes occur in the DNA of breast cancer cells that have developed a resistance to hormone therapy, an effective treatment for ER+ breast cancer, which accounts for 70% of all diagnoses.

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The Importance of Understanding Target–Protein Interactions in Drug Discovery
Article

You’re unwell, you see a doctor, they prescribe you a medicine… and you take it. But how exactly is that drug having an effect? What is its mechanism of action? Drugs exhibit their effects through specific protein–target interactions. Andrew Lynn, Chief Executive Officer at Fluidic Analytics discusses why understanding protein–target interactions is so important.

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Incidence vs Prevalence
Article

In epidemiology, prevalence and incidence are among the most fundamental measures when it comes to monitoring disease. But do you know what they mean or how and why they are important? This article takes a look at disease prevalence and incidence, what this information tells us and how it can be used.

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Complementary Bonds: Strategic Collaboration Between ELRIG and BPS Announced at Pharmacology 2019
Article

A new collaboration was announced Monday between the British Pharmacological Society (BPS) and scientific not-for-profit The European Laboratory Research & Innovation Group (ELRIG) UK at the annual Pharmacology 2019 meeting in Edinburgh, Scotland.

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The Pursuit of Spotting and Steering Cell Death
Article

Here, we examine one common branch of cell death, apoptosis, and explain why studying aberrations in apoptotic signaling is important for understanding and addressing a range of human pathologies. We also highlight techniques that enable studies of apoptosis.

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Should Infectious Diseases Be Made Notifiable? The Good, the Bad and the Ugly
Article

At first glance this question might seem like a no-brainer. Surely if you make an infectious disease notifiable then you are better able to contain infection and prevent it spreading, right? Unfortunately, whilst the principle seems simple, the reality is far less so. Here we take a look at the different facets and implications of making an infectious disease notifiable.

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The Power of Collaboration: Tackling Pharmaceutical Challenges
Article

In this article, we explore how pharmaceutical companies have started to embrace a more collaborative way of working as part of a movement to help overcome some of the challenges the industry is facing.

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