Application Notes

 
A No-Wash 4-Plex Apoptosis Screening Kit and Validation for Phenotypic Screening
Application Note

Since it is so closely related to the overall health of a cell and fundamentally involved in all of cell biology, the need for characterizing apoptosis and apoptotic processes occurs throughout the drug discovery process, from primary screening to toxicity profiling.

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Turn Subtle Phenotypic Responses into Robust Discoveries
Application Note

Today’s drug discovery strategies require candidate compounds to fail early and cheaply in the discovery stage, rather than late and expensively in the clinical phase. Testing compounds in physiologically relevant model systems and leveraging information from image-based screens are ways to focus on those compounds that give rise to the right phenotypic changes without undesirable effects on the system.

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Therapeutic Antibodies: Engineering and Production
Application Note

This infographic highlights the different types of approved antibody drugs and gives an overview of antibody engineering and production.

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Rapid Development of a 9 component Multivariate Calibration for the analysis of Metabolites in Chemically Defined Cell Culture Media
Application Note

This study assessed the performance of the HyperFlux™ PRO Plus Raman Spectroscopy System (Tornado Spectral Systems) for the quantitative analysis of biochemical components in a simplified chemically defined pseudo growth medium for mammalian cell culture.

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Measuring Highly Concentrated Biologics
Application Note

Lunatic accurately measures highly concentrated biologics in a dilution-free, accurate and high-throughput way.

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A Go-to Solution for Visualizing and Analyzing Data [Case Study]
Application Note

In this case study, learn how a multinational pharmaceutical company has expanded data analytics capabilities for 5000 users, starting with a small group in R&D, to early clinical trials, clinical trial development, safety, regulatory, and more.

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Fast, Easy Dual Phosphoprotein Target Analysis
Application Note

Download this application note to learn how the Alpha Terbium SureFire® Ultra™ Multiplex can help get you to your next breakthrough, faster.

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Ready for the New Focus on Data Integrity?
Application Note

This paper outlines the requirements of 21 CFR Part 11 and Annex 11, and provides information on how LabVantage software supports customers in complying with the regulations.

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Sample Prep: The Forgotten Dimension in HPLC
Application Note

Although often forgotten, sample preparation is the most important factor in achieving reproducibility from even the most advanced chromatographic methods. In this paper, you can learn about some ways that sample preparation can affect the selectivity, sensitivity and reproducibility of an analysis.

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Practical Tips for MicroCal PEAQ-ITC Experiments
Application Note

Malvern Instruments has comprehensive manuals and videos to support the use of MicroCal PEAQ-ITC and data analysis.

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