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Latest App Notes & Case Studies

App Note / Case Study

Achieve Next Level Sensitivity for the Evolution of Routine Bioanalysis

Sample preparation and alternative chromatography techniques are often used to meet the sensitivity needs required in routine bioanalytical assays, but these methods can be time consuming.
App Note / Case Study

Cyclic Peptide Quantitation in Human Plasma

In biotherapeutic development, decreased drug doses and limited sample volumes require higher quantification sensitivity, while the complexity of biological matrices calls for the need of assay selectivity improvement.
App Note / Case Study

Early Screening of Pancreatic Cancer Immunotherapy Target Candidates

It has proven difficult to accurately identify the biological targets of cancer, which are necessary for the development of successful therapeutics including novel immunotherapies, such as those based on chimeric antigen receptor (CAR) T cells.
App Note / Case Study

Accelerating Target Validation for Therapeutics With Engineered Cell Libraries

One approach to develop drugs for infectious diseases involves a comprehensive understanding of human-pathogen protein interactions, as targeting host proteins helps reduce the possibility of drug resistance by creating a more significant evolutionary barrier for the virus.
App Note / Case Study

Top Five Reasons To Consider Fully-Automated Enzyme Assays

Download this app note to discover reasons why you should consider fully automated enzyme analysis.
App Note / Case Study

Gene Modification for Cell Therapy Applications

The clinical success of CAR T-cell therapy has spurred increased interest and investments in the advanced therapeutics industry.
App Note / Case Study

Kinetic Curvature: Assessment of Small Molecule Kinetics and Affinity

Surface plasmon resonance (SPR) is a core technology used in many pharma and biotechnology settings for this purpose, however traditional initial SPR screening of weak affinity compounds using a single fixed concentration injection can present numerous challenges.
App Note / Case Study

CRISPR Engineered Cells Enable Variant Disease Modeling

Comprehensive disease modeling can be challenging for many labs due to variations in reagents, cell culture conditions, technical inconsistencies across protocols and experiments and bandwidth limitations.
App Note / Case Study

Analysis of Lipid Nanoparticle Composition

In recent years, interest in lipid nanoparticle (LNP) research has increased due to promising opportunities for RNA-based therapy and gene-editing technology, and LNPs are showing promise as nucleic acid delivery vehicles in the pharmaceutical industry.
App Note / Case Study

Expansion of Specific Lymphocyte Populations

Expansion of Specific Lymphocyte Populations With 4CellĀ® Nutri-T Xeno-Free, Serum-Free Medium

The success of CAR T-cell therapy requires efficient expansion of specific subpopulations of patient-derived immune cells.
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