Latest Application Notes
Shotgun Proteomics for Unbiased Quantification
Shotgun proteomics has the capacity to deliver in-depth information on the identification, the relative amount, and the modification patterns of ever larger fraction of the proteins present in a sample. This has made it an essential approach in most biological research areas.
Greater Precision for Transformative Drug Discovery
Target identification and characterization are key challenges in drug discovery and begin with identifying the function of a possible therapeutic target and its role in the disease.
Comprehending COVID-19: Peptide Mapping of the SARS-CoV-2 Spike Protein
The SARS-CoV-2 spike protein has rightly garnered attention as a leading candidate for protein-based vaccines for COVID-19. Multiple studies have shown that neutralizing antibodies bind to the spike protein at both peptide and peptidoglycan epitopes.
Monitoring T-Cell Exhaustion and Effects of Immunotherapy
The efficient monitoring of T-cell surface markers, cytokines and expression patterns is critical to the study of further immunotherapies. Download this app note to discover how cell analyzers can help.
The Analysis of Pharmaceuticals Using Dual Injection (U)HPLC
Many people pursue ideas of “efficiency” as an ideal for daily life — ideas include how many tasks we can accomplish in a short time frame and how we can minimize our impact on the environment. The same can be true with high performance liquid chromatography (HPLC).
Maintaining the Health and Viability of Cells
Cell culture can be a challenging process because cells are influenced by many factors including how they are physically handled and the labware used to seed and feed cultures.
Improve Recovery of Critical Protein Samples
Protein loss during sample preparation can be an obstacle to reliable product quantitation in all biopharmaceutical settings. Samples are often prepared from feedstocks containing insoluble particles and therefore require a solid-liquid separation before analysis to protect analytical instruments.
Collaboration Delivers Pharma Efficiencies, Data Compliance and Weighing Excellence
Time is a precious commodity and with ever-increasing regulatory scrutiny, pharmaceutical laboratories are always on the lookout for simple solutions to make their routine tasks easier. Here, we speak with experts to find out how they helping scientists weigh samples in the most efficient yet trusted way to date.
Best Practices for Pipetting 3D Cell Culture Hydrogels
Three-dimensional (3D) cell cultures are of increasing interest in research areas such as stem-cell based therapies and drug discovery. However, preparing 3D cell cultures can be difficult, and poor pipetting technique may lead to high variation in 3D cell culture experiments.
Rapid Mammalian Cell Harvest Without Centrifugation for Antibody Purification
Download this app note to discover a novel system that enables rapid clarification of mammalian cell cultures without the need for centrifugation and has no impact on product quality.