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Assess Small Molecule Kinetics and Affinity in Just One Step

Assess Small Molecule Kinetics and Affinity in Just One Step - image

Fragment-based drug discovery (FBDD) is a popular method for the identification of novel small-molecule drugs. However, traditional FBDD screening methods are based on a primary and a secondary screening. 

A new, innovative surface plasmon resonance (SPR) solution provides higher content information, allowing for confident, rapid characterization of hits in a single step.

This application note demonstrates how reliable binding kinetics and affinity can be obtained from one concentration, increasing sample throughput and saving precious material.

Download this application note to discover:

  • The importance of kinetic and affinity assessment in drug discovery workflows
  • Pre-optimized workflows for robust small-molecule characterization
  • How to obtain binding kinetics from one dynamic injection of a single analyte concentration
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