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Characterize Your Oligos With Confidence

Oligos with Confidence

Oligo synthesis can result in the formation of impurities. Hence, final products must be characterized to ensure they meet quality assurance and control standards.  

While LC/MS methods offer efficient solutions for oligo characterization, ion-pairing reagents can suppress ionization in positive mode polarity and decrease system performance. Therefore, most methods require a dedicated negative mode polarity system.

Discover an effective method for LC separation and high-resolution mass data collection that is free from ion-pairing reagents.

Download this app note to learn how you can:

  • Achieve precise and accurate QC without the need for extensive system maintenance and cleaning
  • Separate a wide variety of sample types in only 15 minutes 
  • Achieve excellent retention time reproducibility and faster system re-equilibration

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