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Characterize Your Oligos With Confidence

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Oligo synthesis can result in the formation of impurities. Hence, final products must be characterized to ensure they meet quality assurance and control standards.  

While LC/MS methods offer efficient solutions for oligo characterization, ion-pairing reagents can suppress ionization in positive mode polarity and decrease system performance. Therefore, most methods require a dedicated negative mode polarity system.

Discover an effective method for LC separation and high-resolution mass data collection that is free from ion-pairing reagents.

Download this app note to learn how you can:

  • Achieve precise and accurate QC without the need for extensive system maintenance and cleaning
  • Separate a wide variety of sample types in only 15 minutes 
  • Achieve excellent retention time reproducibility and faster system re-equilibration

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