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Convenient Customization of Your Cation Exchange Analysis

Convenient Customization of Your Cation Exchange Analysis content piece image

Therapeutic monoclonal antibodies (mAbs) are highly heterogeneous molecules due to being composed of a large number of variants. When the variants are present in the pharmaceutical protein, it is possible their biological activity could be altered.

Hence, the microheterogeneity of the mAbs is subject to extensive analytical characterization to ensure safety and efficacy of the biopharmaceutical.

Download this app note to discover a liquid chromatography system for charge variant analysis that:

  • Delivers highly reliable and reproducible results
  • Simplifies the bioanalysis workflow
  • Reduces the time required for buffer preparation