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Protein Sequence Analysis: Next-Generation vs Mass Spectrometry Methods

Protein Sequencing
Credit: iStock

Mass spectrometry is regarded as the gold standard for protein identification; however, this technique cannot easily discriminate between protein variants and modifications, and is not accessible to everyday scientists due to the high cost, space and expertise required.

A novel next-generation protein sequencing platform provides novice and expert users with deeper proteomic insights more conveniently and at a lower relative cost. Using an accessible benchtop instrument, a simple workflow, and cloud-based analysis software, researchers can characterize complex protein samples with greater accuracy and ease. 

This app note compares the utility of next-generation and mass spectrometry-based approaches for the identification and analysis of a range of protein sequences. 

Download this app note to discover:

  • Solutions for deeper proteoform, variant and modification analyses
  • Methods for the easy interpretation of results
  • Enhanced discovery power in proteomic studies 

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