Latest Articles
Sensitivity vs Specificity
ArticleWhen developing diagnostic tests or evaluating results, it is important to understand how reliable those tests and therefore the results you are obtaining are. By using samples of known disease status, values such as sensitivity and specificity can be calculated that allow you to evaluate just that.
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Post-translational Modifications in Biopharmaceuticals
ArticleThis article provides insights on the impact of post-translational modifications of biopharmaceutical products on drug development and biotherapeutic formulation.
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Addressing the Underrepresentation of Women in Science
ArticleWe recently spoke with Jessica Wade, PhD, a physicist at Imperial College London to learn more about her extraordinary efforts to raise the profile of female scientists and other underrepresented groups in science.
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Incentivizing Drug Development for Rare Diseases
ArticleOn Rare Disease Day 2019, we discuss how regulatory incentives are necessary for encouraging rare disease drug development, and share the testimonial videos from this year's international campaign.
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The Hunt for Therapeutic Antibodies
ArticleGiven the clinical success that antibodies (formerly known as “magic bullets”) have facilitated, the drug discovery field continues to search for new therapeutic candidates. This article highlights several techniques used in the process, and touches on current trends driving the field.
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Pharmaceutical R&D Powered by MALDI Mass Spectrometry Imaging
ArticleIn order to design and develop new pharmaceutical compounds, the distribution of drugs and their metabolites in tissues must be determined. The emergence of advanced mass spectrometry techniques, such as MALDI imaging, have been pivotal in advancing the field.
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How Genomics is Shaping Advanced Therapeutics
ArticleGenomics technologies are guiding the development of advanced therapy medicinal products, i.e. gene-based, cell-based, and tissue-engineered approaches. This article highlights the progress, challenges and impact of this interdisciplinary branch of medicine.
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Recent Advances in Liquid Biopsy for Cancer
ArticleLiquid biopsies for cancer search for evidence of disease biomarkers, the most common of which include circulating tumor cells, cell-free nucleic acids, exosomes, proteins and phosphoproteins. Read on for insights on advances in the field that could revolutionize clinical oncology practice.
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UK Lung Cancer Diagnostic Services: Time to Step Up
ArticleThe UK’s national health system needs to take a hard look at their priorities and procedures to ensure that rapid advances in molecular diagnostics in lung cancer are translated into a practical service for all patients, according to a report launched at the British Thoracic Oncology Group Annual Conference.
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A Renaissance for Microflow Liquid Chromatography Mass Spectrometry?
ArticleFirst developed in the 1970s, recent developments are making microflow liquid chromatography techniques more robust – enticing researchers to revisit the opportunities it offers for more sensitive, high-throughput analyses requiring smaller sample volumes than standard flow techniques.
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