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Latest Articles

Article

Novel Biotherapeutics for the Treatment of Cancer

Immunotherapies might be stealing the show in cancer biotherapeutics, but it would seem that combining them with other biological agents – DNA or viruses, for example – is the way to seeing dramatic successes in more cancer patients.
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Discipline Convergence and the New Manufacturing Paradigm

In many industries, curiosity-driven research is being replaced by purpose-driven research, as scientists must satisfy market-led specifications. Successful predictive science depends on seamless collaboration, unified workflows, comprehensive knowledge, and standardized data that is available and understandable in context.
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Types of Pollution: Have You Considered Pharmaceutical Waste?

Despite regulation and legislation regarding the methods by which pharmaceutical companies must treat waste water, reports indicate that manufacturers are continuing to discharge untreated or inappropriately treated waste into the environment. The problem is having devastating impacts on human health, the environment and antimicrobial resistance is soaring.
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Reprogramming and iPSC Formation - Then and Now

The ability to create stem cells from non-embryonic cells, through the process of reprogramming, lifted the ethical hindrance and is driving stem cell research in a new direction at a rapid pace.
Microfluidic Method Identifies Rare Antibodies with Therapeutic Potential content piece image
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Microfluidic Method Identifies Rare Antibodies with Therapeutic Potential

A novel microfluidic platform, able to rapidly isolate and identify rare antibodies from a vast repertoire of human B cells, has been developed by scientists. This technology could possess the ability to support and enhance the development of novel vaccines and biopharmaceuticals in the future.
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Developments in Continuous Cell Culture

Continuous cell culture is part of a trend in bioprocessing towards highly productive, streamlined, and interconnected unit operations. While continuous processing has a long history in various industries, regulatory concerns have stalled widespread adoption of continuous bioprocessing. That is beginning to change as the industry acclimates to regulators’ desire for risk- and science-based production decisions.
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The Viral Genome: Moving Beyond Reading Code – Why Not Rewrite It?

Researchers have discovered how to read, decode, and manipulate previously ‘hidden’ viral code. This could open up new opportunities in drug delivery and gene therapy.
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From the lab to the boardroom: An interview with Darlene Solomon Ph.D.

We spoke to Darlene to learn about her reasons for studying science, how she transitioned away from the lab and some of her proudest achievements at Agilent.
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Protein Biotherapeutics: Mass Spectrometry Analysis

Mass spectrometry has evolved as a prevailing technique for both the characterization of biotherapeutics and identification of protein variants and post-translational modifications.
Protein Purification: Chromatography and Scalability in Biopharma content piece image
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Protein Purification: Chromatography and Scalability in Biopharma

Prof. Giorgio Carta provides us with extraordinary insight into the current state of play, factors to consider when 'scaling up’ separation processes, and general challenges and developments when applying chromatographic techniques to bioprocesses.
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