Latest eBooks

Dysfunctional metabolism is associated with a growing number of different disease states. The ability to examine the genes, proteins and pathways that modulate energy metabolism is therefore a promising new avenue for drug discovery.

Greater appreciation for the complex and dynamic connections between metabolic poise and immune cell function enables researchers to monitor and control how metabolic reprogramming and microenvironmental signals affect the function, fate and fitness of immune cells.

Download this eBook to discover new analytical solutions to accelerate AAV-based gene therapy.

Lipid nanoparticles (LNPs) are effective non-viral vectors, which are widely used delivery vehicles for genetic medicines. It is therefore important to understand and limit LNP-related impurities to help ensure genetic product integrity and mitigate risks to patient safety and product efficacy.

Download this eBook to explore how synthetic biology is being utilized in the development of cell and gene therapies, cancer therapeutics and improved food and agriculture production processes.

Oligonucleotide therapeutics are short DNA or RNA molecules that modulate the expression of target RNA for the treatment of diseases. The success of mRNA-based COVID-19 vaccines has brought renewed interest to other nucleic acid drugs, and the oligo therapeutics market is expected to grow by 25–30% in the next five years with over 1,000 oligonucleotide molecules currently in the pipeline.

Download this eBook to learn more about what’s next for mRNA vaccines,
scaling up in vitro transcription for mRNA production, tools for mRNA analysis
plus the future of mRNA technology.

Cell-based assays offer extensive advantages across multiple fields of research, advantages that can be maximised by the specialised features and high throughput capabilities of microplate readers.

Download this eBook to discover how a Laboratory Information Management System (LIMS) can help you to efficiently manage your lab.

In the “Quality by Design” approach for monoclonal antibody (mAb)-based therapeutics development, stability characterization—the probability of a protein unfolding—is performed to ensure that structure and function are preserved throughout development and manufacturing.