Dr. Zulema Romero Garcia
Assistant Adjunct Professor
at UCLA
Dr. Romero received her Ph.D. from the University Granada (Spain) in 2009 and completed her postdoctoral fellowship work with Dr. Donald Kohn in 2015 at UCLA. During her postdoctoral fellowship she trained in experimental hematology, viral vectors, gene editing methods, and GMP cell processing. She is currently an Assistant Adjunct Professor in the Department of Microbiology, Immunology and Molecular Genetics at UCLA. Currently her central research work aims enhancing gene editing by investigating efficacy and toxicity from the editing protocols; studying the relationship between HSC cell cycle status and gene editing outcomes and engraftment of the long-term HSC in different immunodeficient mouse models; and translating the research-scale methods of editing to GMP-compatible, clinical scale manufacturing. While the field of Gene Editing of HSC is constantly advancing, it is her interest to study new gene editing method, such as Base Editing of DNA to correct monogenic disorders; and RNA Base editing to transiently inhibit the transcripts of genes implicated the DNA damage response pathway triggered after gene editing to improve long-term engraftment of the edited HSPC.
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