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Latest How To Guides

How To Guide

CRISPR Yeast: Replacing the Need for Plant-Derived Metabolites

Plant-derived compounds are widely used across the pharmaceutical, cosmetics, food and agricultural industries. However, compared to other natural compounds, they often produce a lower yield of secondary metabolites.
How To Guide

High-Throughput Nanowell-Based Image Verified Cloning for Cell Line Development

High-throughput nanowell-based image-verified cloning technology (HT-NIC) is a new method allowing the fast generation of clonal pharmaceutical production cell lines.
How To Guide

An Introduction to Miniaturization in NGS Workflows

Download this Guide to explore how NGS can benefit from the miniaturization and automation of library preparation workflows.

A gloved hand holds a conical flask containing water. A glass pipette containing water can be seen to the left. In the background there are many test tubes.
How To Guide

Maintaining Water Quality in the Lab – Key Considerations

Download this guide to explore different water types and their uses, the implications of poor water quality and water storage.
How To Guide

Nitrosamine Impurity Analysis Solutions Guide

Since the discovery of elevated levels of nitrosamines in certain pharmaceuticals, reported in July 2018, finding the right solutions have become a major focus for many pharmaceutical manufacturers, particularly as they are considered probable human carcinogens.
How To Guide

Analytical Solutions for mRNA Vaccines and Therapeutics

Messenger RNA (mRNA) therapy enables the body to make the proteins needed to prevent, treat or cure diseases but, unlike traditional biologics, mRNAs are large and delicate molecules that need to be protected by lipid nanoparticles (LNPs) on the journey to reach target cells.
How To Guide

How To Build an Effective Protein Degrader

This guide highlights the four major stages of targeted protein degradation, the challenges at each step, and the questions you should ask yourself to ensure your final product will result in a complete protein degradation.
How To Guide

The Growing Importance of Mitochondrial Toxicity Assessment in Drug Discovery and Development

The pharmaceutical industry spent decades bringing several drugs to the market, only to be withdrawn due to liver failure, associated with mitochondrial toxicity. The tests available at the time could not detect this toxicity and drug developers were presented a market withdrawal risk.
How To Guide

How to Future Proof Your Laboratory Informatics Environment

Download this guide to learn more about laboratory automation and the novel informatics solutions available to ensure sound and long-lasting investments.
How To Guide

Connecting Laboratories With Data-Driven Automation Software

Download this guide to learn more about automated software and the latest solutions available.
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