Exploring Methods for Host Cell Protein Analysis

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Last Updated: January 7, 2020

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Biotherapeutics now represent a large proportion of therapeutics available on the market. The host systems often used to manufacture protein-based biotherapeutics can produce their own endogenous proteins, known as host cell proteins (HCPs), which can ultimately contaminate the product.

Download this list to learn about some of the most commonly used methods for HCP analysis, including:

ELISA
Western blot
Proximity ligation assay
Mass spectrometry

Meet the Author

Molly Coddington

Senior Science Writer

In the editorial team Molly reports on a broad range of scientific topics, covering the latest breaking news and writing long-form pieces for The Scientific Observer. She is a fervent believer that science – and science communications – should be accessible to everyone. In 2020, she created the Teach Me in 10 video series, where weekly guests discuss and teach a scientific concept in less than 10 minutes. Prior to joining Technology Networks in 2019, Molly worked as a clinical research associate in the NHS and as a freelance science writer. She has a first-class honors degree in neuroscience from the University of Leeds and received a Partnership Award for her efforts in science communication.