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Druggable Protein’s Role in Obesity and Diabetes Defined
Researchers have identified a novel signaling molecule that could lead to the development of novel therapeutics for the prevention and treatment of obesity and diabetes.

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Personalized mRNA Vaccine Could Be Used To Treat Pancreatic Cancer
An research team have been developing a personalized mRNA cancer-treatment vaccine approach. It is designed to help immune cells recognize specific neoantigens on patients’ pancreatic cancer cells.

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Insomnia Medication Could Help Those Who Act Out Their Dreams While Sleeping
Mount Sinai researchers have published what they say is the first study to identify a new form of treatment for rapid eye movement (REM) sleep behavior disorder.

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First Oral Drug To Treat Moderate-to-Severe Crohn’s Disease Approved
Data from a Mount Sinai-led phase 3 trial published today in The New England Journal of Medicine show that upadacitinib, a breakthrough, once-daily oral medication, helps patients achieve and maintain clinical and endoscopic remission.

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How Science Can Choose Less Stigmatizing Language
Word choice matters—a lot— when it comes to research. That's the conclusion of a new study that analyzed HIV-related stigmatizing language published in scientific literature from 2010 to 2020.

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CRISPR-Cas Could Reduce the Spread of Antimicrobial Resistance
A new tool which could help reduce the spread of antimicrobial resistance is showing early promise, through exploiting a bacterial immune system as a gene editing tool.

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Novel Culture System Improves Growth of Blood Stem Cells in the Lab
Hematopoietic stem cells can be transplanted into patients to treat various blood disorders, but this usage is limited by barriers to cell growth and expansion in the lab. A new system from the University of Tsukuba may have the answer.

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Vaccine Trial Results Boost Hope of Eliminating Meningitis by 2030
A trial of a new vaccine against meningococcal disease, a cause of meningitis and blood poisoning, has found that it is safe and induces a strong immune response across five strains of meningococcal bacteria: A, C, W, Y and X.

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The Critical Protein Complex That Helps Lassa Virus Infect Human Cells
By comparing the structures of protein complexes from different lineages of the dangerous Lassa virus, a Scripps Research team identified new antibodies and vaccine targets.

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Bacteria Created That Can Synthesize an Unnatural Amino Acid
Researchers have engineered bacteria to produce an unnatural amino acid with a rare functional group that has implications in immune system regulation, providing a foundation for developing future immunotherapies.
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