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A New Way To Identify “Safe Harbors” for Gene Therapies

Scientists have created a tool that can find safe places to introduce genes into human DNA. The tool is an early step in the process to improve the safety and efficacy of gene and cell therapies.
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mRNA Vaccines Protect Against Serious COVID-19 During Pregnancy

The first large, real-world study of the effectiveness of mRNA COVID-19 vaccines during pregnancy found these vaccines, especially two initial doses followed by a booster, are effective in protecting against serious disease in expectant mothers whether the shots are administered before or during pregnancy.
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Mutating a Key Molecule in Bacterial Protein Could Stop Gonorrhoea Infection

Creating a mutation that inhibits how the bacterial pathogen Neisseria gonorrhoeae causes gonorrhea, a common sexually transmitted infection, could offer a new way to prevent and treat the disease, according to researchers in the Institute for Biomedical Sciences at Georgia State University.
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People Infected With COVID-19 Are at an Elevated Risk of Neurological Conditions

The post-COVID brain is at higher risk of developing neurological conditions including movement disorders, strokes, cognitive and memory problems, anxiety and migraines in the first year after infection, according to new research.
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Evolutionary Steps Algae Took To Make Brown Pigments Uncovered

Biologists have unveiled new insights into the evolutionary steps brown algae took to make their novel pigments.
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Newly Discovered Barrier Prevents Immunity From Reaching Smell-Sensing Cells

A previously unknown barrier separates the bloodstream from the smell-sensing cells in mice, likely as a mechanism of protecting the brain, but may hinder the effectiveness of vaccines.
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Engineered Mosquitoes Prevent Transmission of Malaria to Humans

Scientists have engineered mosquitoes that slow the growth of malaria-causing parasites in their gut, preventing transmission of the disease to humans.
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New “Slow Delivery, Escalating Dose” Vaccine Strategy To Help the Body Target HIV

Researchers at La Jolla Institute for Immunology (LJI) have discovered how the immune system can transform into an antibody-making machine capable of neutralizing one of the most elusive viruses out there: HIV.
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Epigenetic Treatment Supports Spinal Cord Regeneration in Mice

In a murine study, weekly treatments with an epigenetic activator aided the regrowth of sensory and motor neurons in the spinal cord when given 12 weeks after severe injury.
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Gene Therapy Target for Polycystic Kidney Disease Discovered

Blocking the inhibition of two genes by deleting a binding site for microRNAs hindered the formation and growth of kidney cysts in autosomal dominant polycystic kidney disease (ADPKD) models, UT Southwestern researchers reported.
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