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Novel Cellular Entry Factor for Viral Vectors Used in Gene Therapy
News   Jan 24, 2020

Researchers led by a team at Massachusetts Eye and Ear have identified a novel cellular entry factor for adeno-associated virus vector (AAV) types--the most commonly used viral vectors for in vivo gene therapy. AAVs are vectors-or vehicles--that are created from a virus that is made harmless by molecular engineering, and have shown promise transporting genetic therapy treatments to affected tissues.

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Vaccine for African Swine Fever Virus Shows Promise
News   Jan 24, 2020

Government and academic investigators have developed a vaccine against African swine fever that appears to be far more effective than previously developed vaccines.

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Biodegradable Nerve Guide Helps Regenerate Damaged Nerves
News   Jan 22, 2020

Scientists have created a biodegradable nerve guide consisting of a polymer tube filled with a growth-promoting protein, glial cell-derived neurotrophic factor, or GDNF. The results in nonhuman primate studies are promising.

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CRISPR Cuts Open New Avenues in CAR T-cell Therapy
News   Jan 22, 2020

According to a study published in the Blood journal, drug profiling and the CRISPR-Cas9 gene editing method have opened new avenues in the development of CAR T-cell therapy, used to treat leukaemia and lymphoma.

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Danger Posed by Whooping Cough Once More
News   Jan 21, 2020

Whooping cough bacteria, potentially deadly in infants, are increasingly evading immunity from the existing vaccine, strengthening calls for a new vaccine to be developed and deployed urgently.

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Progression of Eye and Cardiac Disease Halted by Food Supplement
News   Jan 21, 2020

UNIGE researchers have discovered a new gene that causes blindness and
cardiomyopathy. They have also managed to halt the progression of eye disease and treat cardiac disease by administering a food supplement.

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Studies Point to Important Role for B Cells in Promoting Anti-tumor Immunity
News   Jan 21, 2020

The likelihood of a patient responding to immune checkpoint blockade may depend on B cells in the tumor, located within specialized immune-cell clusters known as tertiary lymphoid structures (TLS), according to researchers at The University of Texas MD Anderson Cancer Center.

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Targeting “DNA Rewiring” To Reduce Breast Cancer Relapse
News   Jan 20, 2020

Epigenetic changes occur in the DNA of breast cancer cells that have developed a resistance to hormone therapy, an effective treatment for ER+ breast cancer, which accounts for 70% of all diagnoses.

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Programmable Nests for Cells
News   Jan 20, 2020

New programmable materials suited for use as substrates in biomedical applications have now been developed, which can be used to create environments in which human stem cells can settle down and further develop.

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"Venome" is Created As Indian Cobra Genome Is Decoded
News   Jan 17, 2020

Scientists report the sequencing and assembly of a high-quality genome of the highly venomous, medically important Indian cobra (Naja naja). Using a combination of cutting-edge genomic technologies, the authors have assembled the most contiguous genome of this iconic venomous snake.

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