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Harnessing T-Cell Biology To Develop Living Drugs
Researcher Leonardo Ferreira, PhD, has described his experience using chimeric antigen receptor (CAR) regulatory T-cells to address the challenge of transplant tolerance.
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Towards an “Off-the-Shelf” Immunotherapy for Cancer
Researchers are one step closer to an “off-the-shelf” cancer immunotherapy that uses rare but powerful immune cells.
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New Technique May Lead to Safer Stem Cell Transplants
Stem cell transplantation is the gold standard of care for blood cancers, but many patients are too fragile to undergo transplants. Now researchers have developed a method of transplantation that does not require radiation or chemotherapy.
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Targeting Malignant Brain Tumors With T Cells
A neoantigen-specific transgenic immune cell therapy for malignant brain tumors has been successfully tested for the first time using an experimental model in mice.
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Understanding Acquired Malaria Immunity for Improving Vaccines
A new study shows that the immunity produced after having contracted the disease is more efficient than if you have been vaccinated against the deadly disease.
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A New Approach for Potentially Treating and Vaccinating Against Alzheimer’s
Scientists have developed a promising new approach to potentially treat Alzheimer’s disease – and also vaccinate against it.
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Ancient Botanical Therapies Tested as Treatments for COVID-19
A multi-center study called MACH-19 (Mushrooms and Chinese Herbs for COVID-19) is assessing whether medicinal mushrooms and Chinese herbs provide therapeutic benefit in treating acute COVID-19 infection.
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Using Nanoparticle T-Cell Engagers To Treat Acute Myeloid Leukemia
Researchers have created nano T-cell engagers (nanoTCEs) using liposomes conjugated to monoclonal antibodies to enable specific binding. They also recreated the bone marrow niche using a 3D culture system and immunocompromised mice to test the nanoTCEs.
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Evidence of COVID Antibodies in Breast Milk of Vaccinated Mothers
Researchers found evidence that mothers with two types of immunity from COVID – disease-acquired and vaccination-acquired – produced breast milk with active SARS-CoV-2 antibodies.
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Next Generation of COVID-19 Vaccines Should Target T Cells, Researchers Say
By designing vaccines that activate immune memory cells, known as T cells, to attack infected cells expressing this part of the virus’s internal machinery, it may be possible to eliminate SARS-CoV-2 at the very outset, thereby helping stop its spread.
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