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SARS-CoV-2: Experimental Antiviral Therapy Could Reduce Viral Load by 99.9%
An international team of scientists has developed an experimental direct-acting antiviral therapy to treat COVID-19. The antiviral approach used gene-silencing RNA technology known as siRNA (small-interfering RNA) to attack SARS-CoV-2's genome.
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Anti-Inflammatory Drug Inhibits Resistant Triple-Negative Breast Cancer Cells
Researchers have shown that resistant triple-negative breast cancer cells are inhibited by 6-mercaptopurine and 5-azacitidine.
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A New Way of Predicting COVID-19 Vaccine Efficacy
The early immune response in a person who has been vaccinated for COVID-19 can predict the level of protection they will have to the virus over time, according to analysis from Australian mathematicians, clinicians, and scientists.
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Immunotherapy Combination Aims To Improve Success of Cancer Treatment
A new cancer vaccine could enhance the positive effects of existing immunotherapies and boost the success rate of treatments from 20% to 75%, according to a new study published in Nature Communications.
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Stanford Team Discover an Entirely New Kind of Biomolecule
Researchers have discovered a novel biomolecule, glycoRNA, that could play a significant role in the biology of all living things.
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New Technology Transports the Genes for Therapeutic Agents Directly Into Tumor Cells
A new technology from UZH researchers enables the body to produce therapeutic agents on demand at exactly the point where they are needed. The innovation could reduce the side effects of cancer therapy and help better deliver COVID-19 treatments to the lungs.
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CABYR Isoforms As Targets for Specific Immunotherapy
Calcium-binding tyrosine phosphorylation-regulated protein (CABYR) is considered a cancer testis protein. Researchers evaluate the CABYR isoforms: a/b and c mRNA expression in colorectal cancer to determine if these proteins hold promise as vaccine targets.
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Targeting Therapeutics to Harmful Genes Using Nanoparticles
Chemical engineering researchers have created several different types of nanoparticles and analyzed them for the ability to deliver and protect siRNA-based therapeutics from the body's immune system.
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Personalized Anticancer Vaccine Tested in Mice
Researchers are using mice to show how a combination of peptides and oncolytic viruses, used as an adjuvant, can provide effective immunization against cancer.
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Delaying Second COVID-19 Vaccine Dose May Prevent Deaths, Under Certain Conditions
A study has found that delaying the second dose of covid-19 vaccines, at least for people aged under 65, could result in up to 20% lower mortality, but only under certain conditions.
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