News

The biodistribution of adeno-associated virus (AAV) gene transfer vectors can be measured in nonhuman primates using a new method. The method quantifies whole-body and organ-specific AAV capsids from 1 to 72 hours after administration.

The University of Wisconsin School of Medicine and Public Health and UW Health have developed a tool that incorporates a person’s age and socioeconomic status to prioritize vaccine distribution among people who otherwise share similar risks due to their jobs.

Scientists studying the body’s natural defenses against bacterial infection have identified a nutrient — taurine — that helps the gut recall prior infections and kill invading bacteria, such as Klebsiella pneumoniae. The finding could aid efforts in seeking alternatives to antibiotics.

Researchers have uncovered specific molecular properties of an antimicrobial peptide from the skin of the Australian toadlet that could be exploited in efforts to develop novel synthetic drugs to combat bacterial infections.

Ohio State University researchers reviewed 49 vaccine studies in humans dating back 30 years that document how stress, depression and poor health behaviors can negatively affect the body’s immune response to vaccination, and how improving health factors can enhance that response.

Researchers report in ACS Chemical Neuroscience that a compound isolated from the leaves of a traditional medicinal plant, Inula viscosa, kills a "brain-eating" amoebae by causing them to commit cell suicide in lab studies.

In a new study, scientists at Okayama University isolated cardiac stem cells and assessed their potential use as regenerative therapy in young patients with cardiac defects. The team not only showed the effectiveness of the cells in replenishing damaged tissues, but also revealed how this happens.

Scientists have used gene-editing advances to achieve a tenfold increase in the production of super-bug targeting formicamycin antibiotics.

A Caltech team has designed a protein-based 60-subunit nanoparticle onto which pieces of up to eight different types of coronavirus have been attached. When injected into mice, this vaccine induces the production of antibodies that react to a variety of different coronaviruses--including similar viruses that were not presented on the nanoparticle.

Researchers in Umeå have for the first time at the atomic level succeeded in mapping what a virus looks like that causes diarrhea and annually kills about 50,000 children in the world. The discovery may in the long run provide the opportunity for completely new types of treatments for other viral diseases such as COVID-19.