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Researchers made the breakthrough discovery that the genetically encoded T-cell receptor (TCR) sequence that humans develop in early childhood determines a T cell’s function.

Just 20–25 minutes of moderate to vigorous physical activity each day may be enough to combat a highly sedentary lifestyle's increased risk of death, suggests a new study in the British Journal of Sports Medicine.

A new reactor the size of a minifridge that rapidly grows cancer-killing white blood cells could advance the availability of immunotherapy.

Stanford researchers who previously pioneered a new kind of protein degradation have mapped out how the process works, which could lead to new drug therapies for diseases like Alzheimer’s and cancer, and for rare childhood enzyme disorders.

Oxford University Hospitals is now offering CAR-T therapies to people with cancer. The cutting-edge therapy, which uses a patient's own immune cells to create a tailored treatment.

One problem in gene therapy is that not all genes transfer equally well into the target cells. Researchers have now developed a flexible method to transfer large genes efficiently and without significant side effects.

A study of 500 health people has found that antibodies can develop against polyethylene glycol (PEG), a substance used in cosmetics, food and medicine, which might hinder the effectiveness of drugs.

Researchers have loaded extracellular vesicles with therapeutic mRNA, and shown how they can be used to enhance immunotherapy responses in glioblastoma.

Potato starch is being trialed as a dietary intervention to modify the gut microbiome in bone marrow transplant patients, in the hopes of preventing graft-versus-host disease.

A hormone replacement therapy that more closely replicates the natural circadian and ultradian rhythms of our hormones has been shown to improve symptoms in patients with adrenal conditions.