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Therapeutic Cancer Vaccine Demonstrates Good Safety and Efficacy in Preclinical Study
A checkpoint inhibitor vaccine known as PD1-Vaxx was shown to be safe and effective in a colon cancer syngeneic animal model.
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Oxford's COVID-19 Vaccine Has 70% Efficacy Rate
There are now over 170 teams of researchers working to develop a vaccine for protection against COVID-19. Over the last few weeks, a number of groups shared interim analysis data on candidates that have reached Phase III clinical testing. The latest addition is the University of Oxford – in collaboration with the pharmaceutical company AstraZeneca – who today announce an efficacy of 70.4% for the candidate, ChAdOx1 nCoV-2019.
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Metal-Organic Frameworks Successfully Deliver CRISPR/Cas9 Into Human Cancer Cells
Researchers used metal-organic frameworks (MOFs) enhanced with a green tea phytochemical coating to target human prostate cancer cells for the first time.
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Plant Used in Chinese Medicine Has Evolved To Become Less Visible to Humans
Scientists found that Fritillaria delavayi plants, which live on rocky slopes of China's Hengduan mountains, match their backgrounds most closely in areas where they are heavily harvested.
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Potential Cellular Target for Eliminating Bone Breakdown in Osteoporosis Found
New research has discovered a cell type that governs the way bones form and maintain themselves, opening up a potential target for future therapies for bone disorders like osteoporosis.
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COVID-19 Vaccine Distribution Must Include Prison Populations, Study Says
Preventing serious complications from COVID-19 in potentially vulnerable populations in high risk environments, such as prisons, and preventing spread to surrounding communities needs a coordinated evidence-based approach to managing outbreaks of COVID-19 in prison settings.
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Engineered Immune Cells Elicit Broad Response to HIV in Mice
Scientists at Scripps Research moved closer to attaining the holy grail of HIV research with a new vaccine approach that would rely on genetically engineered immune cells from the patient’s body.
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Oxford Coronavirus Vaccine Elicits a Robust Immune Response in Older Adults
Data from the ChAdOx1 nCov-2019 coronavirus vaccine study suggests that one of the groups most vulnerable to serious illness and death from COVID-19, could build robust immunity following vaccination.
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Differing Immune Responses Between Ethnically Divergent Populations Shape Virus Evolution
New research into the HIV-1 virus has shed light on an important factor in virus evolution, which is likely also to affect SARS-CoV-2, that could have important implications for vaccine development.
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CRISPR Gene-Editing System Destroys Cancer Cells in Animal Model
Researchers at Tel Aviv University (TAU) have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers, a significant step on the way to finding a cure for cancer. The researchers developed a novel lipid nanoparticle-based delivery system that specifically targets cancer cells and destroys them by genetic manipulation.
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