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Scientists Use Light To Deliver CRISPR Gene Therapy
Light-activated liposomes could help to deliver CRISPR gene therapy – and the method could prove safer and more direct than current methods.
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What the D614G Mutation Means for SARS-CoV-2 Vaccines
A new study published in Science confirms that SARS-CoV-2 has mutated in a way that’s enabled it to spread quickly around the world, but the spike mutation may also make the virus more susceptible to a vaccine.
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Sputnik V COVID-19 Vaccine Has Efficacy Rate of 92%, Interim Analysis Suggests
The Gamaleya Center and the Russian Direct Investment Fund have announced that Sputnik V – the world's first registered vaccine against COVID-19 – demonstrates an efficacy rate of ~92%.
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Diet-Induced Hepatocyte Regeneration Enhances CRISPR-Mediated Gene Repair
Use of thyroid hormone to boost hepatocyte proliferation enhanced the efficiency of CRISPR/Cas9-mediated gene correction in the mouse liver. This may be a strategy to enhance gene repair within the liver, according to a new study.
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Personalized Cancer Vaccine Trial Set To Expand Following Promising Preliminary Data
A clinical trial designed to study the safety and effectiveness of a personalized cancer vaccine in combination with the immunotherapy drug pembrolizumab will expand its cohort after promising preliminary data was presented.
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Vaccine Combines Cancer-Killing Power of Chemotherapy and Immunotherapy
A new approach to cancer treatment involves chemotherapy and immunotherapy into a biomaterial-based cancer vaccine that can be injected adjacent to a tumor site.
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Protein Involved In Formation and Maintenance of Bacterial Shield Discovered
Scientists reviewed studies of three essential membrane proteins that monitor not only LPS biosynthesis inside the cell, but also transport to, and proper assembly at the cell surface.
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Interim Analysis Suggests SARS-CoV-2 Vaccine Has 90% Efficacy Rate
Pharmaceutical company Pfizer and biotechnology company BioNTech have announced the first interim efficacy data from a large-scale trial evaluating BNT162b2, a vaccine candidate developed against SARS-CoV-2. Their press release indicates a vaccine efficacy rate of ~90% seven days after a second dose of the vaccine is administered, however the data is yet to be published.
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Method Identifies Llama Nanobodies With "Ultra-High" SARS-CoV-2 Neutralization Potency
In Science, researchers at the University of Pittsburgh School of Medicine describe a new method to extract tiny but extremely powerful SARS-CoV-2 antibody fragments from llamas, which could be fashioned into inhalable therapeutics with the potential to prevent and treat COVID-19.
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Key Marker Helps Accelerate the Development of CMV Vaccines
A research team has identified a key marker that will help speed effective vaccine designs for cytomegalovirus (CMV).
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