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In experiments in rats and mice, scientists report the successful use of nanoparticles to deliver gene therapy for blinding eye disease.

Scientists have developed a new approach to immunological tumor treatment. Their method is based on the specific blockade of an immune checkpoint by a stable "mirror-image" peptide.

Scientists have discovered a new target and a new therapy for Nonalcoholic Fatty Liver Disease (NAFLD), that has shown promising results in preclinical mouse models.

Researchers have developed a computational model that helps improve the injectability of microparticles and prevent them from clogging.

A common inherited genetic variant is a frequent cause of deafness in adults, meaning that many thousands of people are potentially at risk, reveals research.

Using an animal model, researchers have demonstrated that age-related frailty and immune decline can be halted and even partially reversed using a novel cell-based therapeutic approach.

BUSM researchers have developed and implemented a new way to better understand how human cells communicate with each other, how this communication is disrupted in human diseases and how this can be corrected pharmacologically.

The active ingredients of many drugs are natural products. Similar to the production line in a factory, large enzyme complexes put these active agent molecules together inside microorganisms. A team of researchers has now succeeded in investigating the basic mechanisms of one of these "factories".

The exact process by which uromodulin prevents inflammation had never been understood. Now an interdisciplinary team, drawn from three research groups at ETH Zurich together with researchers from the University of Zurich and the Children's Hospital Zurich, has filled this knowledge gap.

Using state-of-the-art approaches coupled with bio- and cheminformatics and machine learning, researchers at the GEOMAR Helmholtz Centre for Ocean Research Kiel have succeeded in discovering new, bioactive components of the Baltic Sea seaweed Fucus vesiculosus and its fungal symbiont against infectious bacteria or skin cancer.