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New Method of Mapping Molecules on Tumor Cells
Scientists have developed a new way of mapping the molecules on the surface of tumor cells that flag their presence to the immune system.
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Key Mechanism Enables Cancer Cells To Evade the Immune System
Researchers uncover a key mechanism that regulates PD-L1, a protein that helps cancerous cells evade detection by the immune system and is the target of several immunotherapy drugs
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Preprint Suggests MERS-CoV Vaccine Can Protect Monkeys
An investigational vaccine called ChAdOx1 MERS protected two groups of rhesus macaques from disease caused by Middle East respiratory syndrome coronavirus (MERS-CoV). MERS-CoV is a relative of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19).
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Simulations Illustrate How To Make Gene Therapy More Effective
Scientists at the University of Groningen have now used advanced simulations to investigate how lipoplexes deliver DNA fragments into cells. The results, which were published in the journal eLife, can be used to improve their efficiency.
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Nanobodies Facilitate Improved COVID-19 Imaging
Researchers have isolated nanobodies which bind to the “spike” protein of the SARS-CoV-2 virus, which can be used to improve imaging of the virus.
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Partnership To Speed COVID-19 Vaccine and Treatment Options Set To Launch
The National Institutes of Health and the Foundation for the NIH are bringing together leading biopharmaceutical companies, the Health and Human Services Office of the Assistant Secretary for Preparedness and Response, the Centers for Disease Control and Prevention, the U.S. Food and Drug Administration and the European Medicines Agency to develop an international strategy for a coordinated research response to the COVID-19 pandemic.
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Gut Microbe Bile Metabolite Boosts Immune Cells
A Ludwig Cancer Research study has discovered a novel means by which bacterial colonies in the small intestine support the generation of regulatory T cells—immune cells that suppress autoimmune reactions and inflammation.
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Psychedelic Compound Can Be Produced in Yeast
Scientists from DTU Biosustain prove that psilocybin, a potential drug for treating depression and other psychological conditions can be produced in yeast.
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First US Trial Participant Receives Gimsilumab for COVID-19 and Acute Respiratory Distress Syndrome
Temple University Hospital has treated the first BREATHE trial participant in the United States evaluating intravenous treatment with gimsilumab on mortality for patients with COVID-19 and acute respiratory distress syndrome.
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Technique Reduces the Time It Takes To Discover Antibody-based Drugs
New research has resulted in the development of a technique that allows fragments of antibodies to be screened for susceptibility to aggregation much earlier in the drug discovery process.
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